SCHEMBL441631

SCHEMBL441631

CCOc1ccccc1N=C=Nc1ccccc1OCC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
L3MBTL1 Q9Y468 4/20 0.43
MAPT P10636 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
GLA P06280 1/20 0.43
PABPC1 P11940 1/20 0.42
CTDSP1 Q9GZU7 1/20 0.42
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C19 P33261 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
PTPRC P08575 1/20 0.39
GAA P10253 2/20 0.39
HCRTR1 O43613 1/20 0.39
CNR2 P34972 1/20 0.38
HPGD P15428 1/20 0.38
HSD17B10 Q99714 1/20 0.38
ALOX15 P16050 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15805993 0.93 L3MBTL1 (0.49) ALDH1A1L3MBTL1MAPTNPSR1GLA
SCHEMBL30075523 0.85 CYP3A4 (0.47) ALDH1A1L3MBTL1MAPTNPSR1GLA
SCHEMBL1021154 0.85 CYP3A4 (0.47) ALDH1A1L3MBTL1MAPTNPSR1GLA
SCHEMBL3976569 0.85 ALDH1A1 (0.46) ALDH1A1L3MBTL1MAPTNPSR1GLA
SCHEMBL18944252 0.82 ALDH1A1 (0.50) ALDH1A1L3MBTL1MAPTNPSR1GLA
SCHEMBL49553 0.81 ALDH1A1 (0.54) ALDH1A1L3MBTL1MAPTNPSR1GLA
SCHEMBL11695265 0.81 ALDH1A1 (0.54) ALDH1A1L3MBTL1MAPTNPSR1GLA
SCHEMBL160030 0.80 ALDH1A1 (0.39) ALDH1A1L3MBTL1MAPTNPSR1GLA
SCHEMBL11710514 0.78 ALDH1A1 (0.50) ALDH1A1L3MBTL1MAPTNPSR1GLA
SCHEMBL5534472 0.78 ALDH1A1 (0.50) ALDH1A1L3MBTL1MAPTNPSR1GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8247156-B2 Processes for producing polyester latexes with improved hydrolytic stability XEROX CORPORATION (US) 2012-08-21 US claimed
US-20120064453-A1 PROCESSES FOR PRODUCING POLYESTER LATEXES WITH IMPROVED HYDROLYTIC STABILITY XEROX CORPORATION (US) 2012-03-15 US claimed
US-9493691-B2 Moisture curable organopolysiloxane compositions MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2016-11-15 US disclosed
US-20160060494-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITIONS MOMENTIVE PERFORMANCE MATERIALS INC. 2016-03-03 US disclosed
EP-2969996-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITIONS Momentive Performance Materials Inc. (US) 2016-01-20 EP disclosed
WO-2014163917-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITIONS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2014-10-09 WO disclosed
US-20130082556-A1 HYDRODYNAMIC DISC DRIVE SPINDLE MOTOR HAVING HYDRO BEARING WITH LUBRICANT SEAGATE TECHNOLOGY LLC (US) 2013-04-04 US disclosed
EP-2290043-B1 A lubricating oil composition comprising metal dialkyldithiophosphate and carbodiimide INFINEUM INT LTD (GB) 2012-08-29 EP disclosed
US-8247156-B2 Processes for producing polyester latexes with improved hydrolytic stability XEROX CORPORATION (US) 2012-08-21 US disclosed
US-20120068564-A1 HYDRODYNAMIC DISC DRIVE SPINDLE MOTOR HAVING HYDRO BEARING WITH LUBRICANT SEAGATE TECHNOLOGY LLC (US) 2012-03-22 US disclosed
US-20120064453-A1 PROCESSES FOR PRODUCING POLYESTER LATEXES WITH IMPROVED HYDROLYTIC STABILITY XEROX CORPORATION (US) 2012-03-15 US disclosed
EP-1121405-B1 METHOD FOR PRODUCING LUBRICATING OILS WITH ANTI RUST PROPERTIES EXXONMOBIL RES & ENG CO (US) 2003-05-07 EP disclosed
EP-0992571-B1 Lubricating oils of enhanced oxidation stability EXXONMOBIL RES & ENG CO (US) 2002-12-18 EP disclosed
EP-1123366-A1 POLAR OIL BASED INDUSTRIAL OILS WITH ENHANCED SLUDGE PERFORMANCE ExxonMobil Research and Engineering Company (US) 2001-08-16 EP disclosed
US-6235687-B1 MIXTURES EXXON RESEARCH AND ENGINEERING COMPANY 2001-05-22 US disclosed
US-6143702-A ACTS SYNERGISTICALLY TO EXTEND OXIDATION LIFE OF MINERAL OILS ESPECIALLY THOSE MINERAL OILS OF HIGH SATURATES CONTENT SUCH AS CATALYTICALLY HYDROGENATED OILS INCLUDING HYDROCRACKED, HYDROTREATED, HYDROFINED, HYDROISOMERIZED OILS EXXON RESEARCH AND ENGINEERING COMPANY (US) 2000-11-07 US disclosed
WO-2000022071-A1 POLAR OIL BASED INDUSTRIAL OILS WITH ENHANCED SLUDGE PERFORMANCE EXXON RESEARCH AND ENGINEERING COMPANY (US) 2000-04-20 WO disclosed
EP-0992571-A1 Lubricating oils of enhanced oxidation stability EXXON RESEARCH AND ENGINEERING COMPANY (US) 2000-04-12 EP disclosed
US-4202786-A Peroxygen bleaching and compositions therefor FMC CORPORATION (US) 1980-05-13 US disclosed
US-4113676-A Aqueous dispersions of esters stabilized with carbodiimides PPG INDUSTRIES, INC. (US) 1978-09-12 US disclosed