Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 20/20 | 0.80 |
| ▸ | HTR7 | P34969 | 2/20 | 0.66 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.66 |
| ▸ | HTR1A | P08908 | 1/20 | 0.64 |
| ▸ | HTR2C | P28335 | 1/20 | 0.64 |
| ▸ | HTR2B | P41595 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6187833 | 0.89 | HTR6 (1.00) | HTR6HTR7HTR4 | |
| SCHEMBL6185827 | 0.89 | HTR6 (0.84) | HTR6HTR7HTR4HTR1AHTR2C | |
| SCHEMBL6187019 | 0.88 | HTR6 (1.00) | HTR6HTR7HTR1AHTR2CHTR2B | |
| SCHEMBL6184883 | 0.88 | HTR6 (1.00) | HTR6HTR7HTR4 | |
| SCHEMBL6188309 | 0.88 | HTR6 (1.00) | HTR6HTR7HTR4 | |
| Hydrochloric Acid SCHEMBL6186936 | 0.88 | HTR6 (0.82) | HTR6HTR7HTR4HTR1AHTR2C | |
| Hydrochloric Acid SCHEMBL6186589 | 0.88 | HTR6 (0.98) | HTR6HTR7HTR4 | |
| Hydrochloric Acid SCHEMBL6191265 | 0.87 | HTR6 (0.98) | HTR6HTR7HTR4 | |
| Hydrochloric Acid SCHEMBL6188087 | 0.87 | HTR6 (0.98) | HTR6HTR7HTR1AHTR2CHTR2B | |
| SCHEMBL6190119 | 0.87 | HTR6 (0.77) | HTR6HTR7HTR4HTR1AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090054489-A1 | Multimediator Dopamine Transport Inhibitors, and Uses Related Thereto | PREXA PHARMACEUTICALS, INC. (US) | 2009-02-26 | — | — | US | disclosed |
| EP-1893202-A2 | MULTIMEDIATOR DOPAMINE TRANSPORT INHIBITORS, AND USES RELATED THERETO | PREXA PHARMACEUTICALS, INC. (US) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006091702-A2 | MULTIMEDIATOR DOPAMINE TRANSPORT INHIBITORS, AND USES RELATED THERETO | PSYCHENOMICS, INC. (US) | 2006-08-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054489-A1 | Multimediator Dopamine Transport Inhibitors, and Uses Related Thereto | SLC6A2, SLC6A3, SLC6A4 | HTR6 14/4885HTR7 17/4885HTR4 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.