⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8616259 | 0.82 | — | — | |
| SCHEMBL6479631 | 0.80 | KDM4E (0.35) | — | |
| SCHEMBL9819931 | 0.76 | — | — | |
| SCHEMBL7600118 | 0.74 | — | — | |
| SCHEMBL1304032 | 0.72 | CYP2A6 (0.31) | — | |
| SCHEMBL709852 | 0.71 | MAPT (0.39) | — | |
| SCHEMBL1781175 | 0.69 | — | — | |
| SCHEMBL1162789 | 0.63 | — | — | |
| SCHEMBL20924 | 0.63 | PARP1 (0.35) | — | |
| SCHEMBL22635712 | 0.63 | GAA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 300 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108156812-B | Improved olefin metathesis catalysts | 卑尔根技术交易股份公司 | 2022-09-30 | — | — | CN | claimed |
| EP-2603508-B1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2019-03-13 | — | — | EP | claimed |
| US-9924721-B2 | Malonic ester derivatives of heteroarylpiperidines and -piperazines as fungicides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-03-27 | — | — | US | claimed |
| EP-3013821-B1 | PIPERIDINECARBOXYLIC ACID DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2018-03-14 | — | — | EP | claimed |
| EP-3241829-A1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | Bayer Intellectual Property GmbH (DE) | 2017-11-08 | — | — | EP | claimed |
| EP-2563786-B1 | Ketoheteroarylpiperidine and piperazine derivatives as fungicides | BAYER IP GMBH (DE) | 2016-11-02 | — | — | EP | claimed |
| US-20160198713-A1 | Malonic ester derivatives of heteroarylpiperidines and -piperazines as fungicides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-07-14 | — | — | US | claimed |
| US-9357779-B2 | Ketoheteroarylpiperdine and -piperazine derivatives as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-06-07 | — | — | US | claimed |
| US-20160135461-A1 | PIPERIDINECARBOXYLIC ACID DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-05-19 | — | — | US | claimed |
| EP-2376487-B1 | THIAZOLYL OXIME ETHER AND HYDRAZONES AS PLANT PROTECTION AGENT | BAYER IP GMBH (DE) | 2016-01-06 | — | — | EP | claimed |
| EP-2272846-A1 | Thiazolylpiperidine derivatives as fungicide | Bayer CropScience AG (DE) | 2011-01-12 | — | — | EP | claimed |
| WO-2010149275-A1 | THIAZOLYLPIPERIDINE DERIVATES AS FUNGICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-12-29 | — | — | WO | claimed |
| US-20100190828-A1 | Thiazolyl oxime ethers and hydrazones as crop protection agents | BAYER CROPSCIENCE AG (DE) | 2010-07-29 | — | — | US | claimed |
| WO-2010066353-A1 | THIAZOLYL OXIME ETHER AND HYDRAZONES ASL PLANT PROTECTION AGENT | BAYER CROPSCIENCE AG (DE) | 2010-06-17 | — | — | WO | claimed |
| US-20100137245-A1 | Heteerocyclyl-substituted thiazoles as crop protection agents | BAYER CROPSCIENCE AG (DE) | 2010-06-03 | — | — | US | claimed |
| WO-2010037479-A1 | HETEROCYCLYL-SUBSTITUTED THIAZOLES AS PLANT PROTECTION AGENTS | BAYER CROPSCIENCE AG (DE) | 2010-04-08 | — | — | WO | claimed |
| US-20090118320-A1 | DERIVATIVES OF 5,9-METHANOCYCLOOCTA[B]PYRIDIN-2-(1H)-ONE, THEIR PREPARATION AND USE AS ANALGESICS | ZHANG HESHENG | 2009-05-07 | — | — | US | claimed |
| EP-2044937-A1 | ANALGESIC 5, 9 - METHANOCYCLOOCTA (b) PYRIDIN - 2 (1H) - ONE DERIVATIVES, THEIR PREPARATION METHOD AND USE | Tianjin Hemey Bio-Tech Co., Ltd. (CN) | 2009-04-08 | — | — | EP | claimed |
| US-5114949-A | Treating disorders associated with 5HT uptake | RHONE-POULENC SANTE (FR) | 1992-05-19 | — | — | US | claimed |
| EP-0429341-A2 | Heterocyclic derivatives, their preparation and pharmaceuticals containing them | RHONE-POULENC SANTE (FR) | 1991-05-29 | — | — | EP | claimed |