⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL441664 | 0.76 | — | — | |
| SCHEMBL6526220 | 0.76 | — | — | |
| SCHEMBL709852 | 0.69 | MAPT (0.39) | — | |
| SCHEMBL22635712 | 0.67 | GAA (0.33) | — | |
| SCHEMBL22635713 | 0.67 | GAA (0.33) | — | |
| SCHEMBL8616259 | 0.65 | — | — | |
| SCHEMBL29595470 | 0.64 | — | — | |
| SCHEMBL9178868 | 0.64 | — | — | |
| SCHEMBL6479631 | 0.64 | KDM4E (0.35) | — | |
| SCHEMBL1162789 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987132-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| EP-0279681-A2 | Saturated heterocyclic carboxamide derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-08-24 | — | — | EP | disclosed |