Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6526220 | 0.80 | — | — | |
| SCHEMBL441664 | 0.80 | — | — | |
| SCHEMBL18262008 | 0.78 | KDM4E (0.33) | KDM4EMEN1ALDH1A1LMNABCHE | |
| SCHEMBL10522276 | 0.73 | CDC25B (0.50) | KDM4EMEN1ALDH1A1LMNABCHE | |
| SCHEMBL2722880 | 0.70 | KDM4E (0.33) | KDM4EMEN1ALDH1A1LMNABCHE | |
| SCHEMBL3769766 | 0.68 | MEN1 (0.55) | KDM4EMEN1ALDH1A1LMNABCHE | |
| SCHEMBL568780 | 0.66 | MEN1 (0.46) | KDM4EMEN1ALDH1A1LMNABCHE | |
| SCHEMBL504078 | 0.66 | MEN1 (0.46) | KDM4EMEN1ALDH1A1LMNABCHE | |
| SCHEMBL8616259 | 0.65 | — | — | |
| SCHEMBL1304032 | 0.65 | CYP2A6 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050096491-A1 | Aromatic methylidene compound, methylstyryl compound for producing the same, production method therefor, and organic electroluminescent element | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 2005-05-05 | — | — | US | disclosed |
| US-20040115475-A1 | Aromatic methylidene compound, methylstyrul compound for producing the same, production electroluminescent element | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 2004-06-17 | — | — | US | disclosed |
| US-20030224206-A1 | Aromatic methylidene compound, methylstyryl compound for producing the same, production method therefor, and organic electroluminescent element | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. | 2003-12-04 | — | — | US | disclosed |
| EP-0089759-B1 | DIBENZOCYCLOHEPTENYLIDENE COMPOUNDS FOR USE IN MODULATING THE IMMUNE RESPONSE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1986-04-09 | — | — | EP | disclosed |
| EP-0089759-B1 | DIBENZOCYCLOHEPTENYLIDENE COMPOUNDS FOR USE IN MODULATING THE IMMUNE RESPONSE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1986-04-09 | — | — | EP | disclosed |
| EP-0035903-B1 | DIBENZOCYCLOHEPTENYLIDENES AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1984-10-17 | — | — | EP | disclosed |
| EP-0035903-B1 | DIBENZOCYCLOHEPTENYLIDENES AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1984-10-17 | — | — | EP | disclosed |
| EP-0115690-A1 | Dibenzocycloheptenylidenes | AMERICAN HOME PRODUCTS CORPORATION (US) | 1984-08-15 | — | — | EP | disclosed |
| EP-0115690-A1 | Dibenzocycloheptenylidenes | AMERICAN HOME PRODUCTS CORPORATION (US) | 1984-08-15 | — | — | EP | disclosed |
| EP-0089759-A1 | Dibenzocycloheptenylidene compounds for use in modulating the immune response | AMERICAN HOME PRODUCTS CORPORATION (US) | 1983-09-28 | — | — | EP | disclosed |
| EP-0089759-A1 | Dibenzocycloheptenylidene compounds for use in modulating the immune response | AMERICAN HOME PRODUCTS CORPORATION (US) | 1983-09-28 | — | — | EP | disclosed |
| US-4376124-A | Method for modulating the immune response with dibenzocycloheptenylidenes | AMERICAN HOME PRODUCTS CORPORATION (US) | 1983-03-08 | — | — | US | disclosed |
| US-4376124-A | Method for modulating the immune response with dibenzocycloheptenylidenes | AMERICAN HOME PRODUCTS CORPORATION (US) | 1983-03-08 | — | — | US | disclosed |
| WO-1981002519-A1 | METHOD FOR TREATING INFLAMMATION | AMERICAN HOME PROD (US) | 1981-09-17 | — | — | WO | disclosed |
| EP-0035903-A1 | Dibenzocycloheptenylidenes and their use in pharmaceutical compositions | AMERICAN HOME PRODUCTS CORPORATION (US) | 1981-09-16 | — | — | EP | disclosed |
| EP-0035903-A1 | Dibenzocycloheptenylidenes and their use in pharmaceutical compositions | AMERICAN HOME PRODUCTS CORPORATION (US) | 1981-09-16 | — | — | EP | disclosed |
| US-4267192-A | BY ADMINISTERING AN UNSATURATED DIBENZOCYCLOHEPTENE ACID OR ESTER COMPOUND | AMERICAN HOME PRODUCTS CORPORATION (US) | 1981-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050096491-A1 | Aromatic methylidene compound, methylstyryl compound for producing the same, production method therefor, and organic electroluminescent element | OR51E2, CYP4F11, ACAD11 | KDM4E 909/4885MEN1 373/4885ALDH1A1 558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.