Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 18/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 4/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4415142 | 0.90 | CCR2 (0.46) | CCR2KCNH2CCR5 | |
| SCHEMBL5030885 | 0.88 | CCR2 (0.51) | CCR2KCNH2CCR5 | |
| SCHEMBL4424621 | 0.85 | CCR2 (0.54) | CCR2KCNH2CCR5 | |
| SCHEMBL4417209 | 0.79 | CCR2 (0.61) | CCR2KCNH2CCR5 | |
| SCHEMBL5117650 | 0.79 | CCR2 (0.57) | CCR2KCNH2CCR5 | |
| SCHEMBL4416873 | 0.78 | DCUN1D1 (0.46) | CCR2KCNH2MEN1KMT2A | |
| SCHEMBL4413543 | 0.77 | CCR2 (0.55) | CCR2KCNH2CCR5 | |
| SCHEMBL4415274 | 0.76 | CCR2 (0.35) | CCR2KCNH2 | |
| SCHEMBL4416767 | 0.76 | CCR2 (0.53) | CCR2KCNH2CCR5 | |
| SCHEMBL4419993 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606255-B1 | CYCLIC DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL MYERS SQUIBB CO (US) | 2009-11-11 | — | — | EP | claimed |