Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCUN1D1 | Q96GG9 | 12/20 | 0.46 |
| ▸ | UBE2M | P61081 | 10/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CCR2 | P41597 | 3/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4422880 | 0.89 | CCR2 (0.51) | DCUN1D1UBE2MMEN1KMT2ACCR2 | |
| SCHEMBL4424621 | 0.89 | CCR2 (0.54) | CCR2KCNH2 | |
| SCHEMBL4415142 | 0.82 | CCR2 (0.46) | CCR2KCNH2 | |
| SCHEMBL4413543 | 0.81 | CCR2 (0.55) | CCR2KCNH2 | |
| SCHEMBL4416767 | 0.80 | CCR2 (0.53) | CCR2KCNH2 | |
| SCHEMBL4416862 | 0.79 | CCR2 (0.64) | CCR2KCNH2 | |
| SCHEMBL4423202 | 0.78 | CCR2 (0.66) | CCR2KCNH2 | |
| SCHEMBL4417518 | 0.78 | CCR2 (0.64) | CCR2KCNH2 | |
| SCHEMBL4417216 | 0.78 | CCR2 (0.41) | MEN1KMT2ACCR2KCNH2 | |
| SCHEMBL4418746 | 0.77 | CCR2 (0.49) | CCR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606255-B1 | CYCLIC DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL MYERS SQUIBB CO (US) | 2009-11-11 | — | — | EP | claimed |
| EP-1606255-B1 | CYCLIC DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL MYERS SQUIBB CO (US) | 2009-11-11 | — | — | EP | disclosed |