Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET2 | Q6N021 | 4/20 | 0.36 |
| ▸ | TET3 | O43151 | 1/20 | 0.36 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5515961 | 0.94 | TET2 (0.35) | TET2TET3TET1TBXAS1GRIK1 | |
| SCHEMBL8743488 | 0.93 | KDM4A (0.33) | TET2TET3TET1 | |
| SCHEMBL11591743 | 0.88 | TET2 (0.39) | TET2TET3TET1GRIK1GRIK2 | |
| SCHEMBL488995 | 0.86 | TET2 (0.33) | TET2TET3TET1TBXAS1GRIK1 | |
| SCHEMBL11573126 | 0.81 | TET2 (0.31) | TET2TET3TET1TBXAS1 | |
| SCHEMBL637535 | 0.81 | TBXAS1 (0.35) | TET2TET3TET1TBXAS1GRIK1 | |
| SCHEMBL5716815 | 0.79 | LMNA (0.43) | — | |
| SCHEMBL3284744 | 0.79 | TBXAS1 (0.37) | TET2TET3TET1TBXAS1 | |
| SCHEMBL6681392 | 0.77 | TET2 (0.32) | TET2TET3TET1TBXAS1GRIK1 | |
| SCHEMBL489029 | 0.76 | CA12 (0.35) | TET2TET3TET1TBXAS1GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0751405-A2 | Balanced charge polymer and hydrophilic contact lens manufactured therefrom | Hydron Limited (GB) | 1997-01-02 | — | — | EP | claimed |
| EP-0751404-A2 | Balanced charge polymer and hydrophilic contact lens manufactured therefrom | Hydron Limited (GB) | 1997-01-02 | — | — | EP | claimed |
| EP-0751407-A2 | Balanced charge polymer and hydrophilic contact lens manufactured therefrom | Hydron Limited (GB) | 1997-01-02 | — | — | EP | claimed |
| US-5391669-A | Lens formed of water swellable crosslinked polymer containing polymer containing cationic-aninoic pair of unsaturated monomers and nonionic monomers | HYDRON LIMITED (GB) | 1995-02-21 | — | — | US | claimed |
| EP-0563299-A4 | BALANCED CHARGE POLYMER AND HYDROPHILIC CONTACT LENS MANUFACTURED THEREFROM | CESKOSLOVENSKA AKADEMIE VED (CS) | 1994-07-20 | — | — | EP | claimed |
| US-5270415-A | Balanced charge polymer and hydrophilic contact lens manufactured therefrom | ALLERGAN INC. (US) | 1993-12-14 | — | — | US | claimed |
| EP-0563299-A1 | BALANCED CHARGE POLYMER AND HYDROPHILIC CONTACT LENS MANUFACTURED THEREFROM | Hydron Limited (GB) | 1993-10-06 | — | — | EP | claimed |
| WO-1992011301-A1 | BALANCED CHARGE POLYMER AND HYDROPHILIC CONTACT LENS MANUFACTURED THEREFROM | ALLERGAN, INC. (US) | 1992-07-09 | — | — | WO | claimed |
| EP-1286823-B1 | OPHTHALMIC LENSES AND COMPOSITIONS, AND METHODS FOR PRODUCING SAME | COOPERVISION INT HOLDING CO LP (BB) | 2009-06-17 | — | — | EP | disclosed |
| US-7262232-B2 | Ophthalmic lenses and compositions and methods for producing same | COOPERVISION, INC. (US) | 2007-08-28 | — | — | US | disclosed |
| US-6992118-B2 | Ophthalmic lenses and compositions and methods for producing same | COOPER VISION INC. (US) | 2006-01-31 | — | — | US | disclosed |
| US-20050191335-A1 | Ophthalmic lenses and compositions and methods for producing same | COOPERVISION INC. (US) | 2005-09-01 | — | — | US | disclosed |
| EP-1286823-A4 | OPHTHALMIC LENSES AND COMPOSITIONS, AND METHODS FOR PRODUCING SAME | OCULAR SCIENCES INC (US) | 2005-01-12 | — | — | EP | disclosed |
| US-20040046932-A1 | Ophthalmic lenses and compositions and methods for producing same | OCULAR SCIENCES, INC. | 2004-03-11 | — | — | US | disclosed |
| EP-0751404-A2 | Balanced charge polymer and hydrophilic contact lens manufactured therefrom | Hydron Limited (GB) | 1997-01-02 | — | — | EP | disclosed |
| US-5391669-A | Lens formed of water swellable crosslinked polymer containing polymer containing cationic-aninoic pair of unsaturated monomers and nonionic monomers | HYDRON LIMITED (GB) | 1995-02-21 | — | — | US | disclosed |
| EP-0563299-A4 | BALANCED CHARGE POLYMER AND HYDROPHILIC CONTACT LENS MANUFACTURED THEREFROM | CESKOSLOVENSKA AKADEMIE VED (CS) | 1994-07-20 | — | — | EP | disclosed |
| US-5270415-A | Balanced charge polymer and hydrophilic contact lens manufactured therefrom | ALLERGAN INC. (US) | 1993-12-14 | — | — | US | disclosed |
| EP-0563299-A1 | BALANCED CHARGE POLYMER AND HYDROPHILIC CONTACT LENS MANUFACTURED THEREFROM | Hydron Limited (GB) | 1993-10-06 | — | — | EP | disclosed |
| WO-1992011301-A1 | BALANCED CHARGE POLYMER AND HYDROPHILIC CONTACT LENS MANUFACTURED THEREFROM | ALLERGAN, INC. (US) | 1992-07-09 | — | — | WO | disclosed |