Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | S100A4 | P26447 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28989937 | 0.74 | PDE4B (0.39) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL28989849 | 0.74 | PDE4B (0.39) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL28989848 | 0.74 | PDE4B (0.39) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL29278506 | 0.74 | PDE4B (0.39) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL28989844 | 0.74 | PDE4B (0.39) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL12355698 | 0.73 | CHRNB2 (0.40) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL29117068 | 0.72 | SIGMAR1 (0.40) | — | |
| SCHEMBL29117092 | 0.72 | SIGMAR1 (0.40) | — | |
| SCHEMBL5916878 | 0.69 | MAPT (0.46) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL17670970 | 0.68 | TDP1 (0.43) | MAPTALDH1A1MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2130820-A1 | Antipruritics | SHIONOGI & CO., LTD. (JP) | 2009-12-09 | — | — | EP | disclosed |