Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 10/20 | 0.59 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | DRD1 | P21728 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2077577 | 0.75 | DRD3 (0.74) | DRD3DRD2 | |
| SCHEMBL29389668 | 0.74 | DRD3 (1.00) | DRD3DRD2DRD1 | |
| SCHEMBL323406 | 0.74 | DRD3 (1.00) | DRD3DRD2DRD1 | |
| SCHEMBL2078437 | 0.74 | DRD3 (1.00) | DRD3DRD2DRD1 | |
| SCHEMBL2080515 | 0.74 | DRD3 (1.00) | DRD3DRD2DRD1 | |
| Hydrochloric Acid SCHEMBL5874342 | 0.73 | DRD3 (0.97) | DRD3DRD2DRD1 | |
| Hydrochloric Acid SCHEMBL2081049 | 0.73 | DRD3 (0.97) | DRD3DRD2DRD1 | |
| Hydrochloric Acid SCHEMBL2081050 | 0.73 | DRD3 (0.97) | DRD3DRD2DRD1 | |
| SCHEMBL969955 | 0.73 | DRD3 (0.74) | DRD3DRD2 | |
| SCHEMBL4689493 | 0.73 | DRD3 (0.51) | DRD3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318451-A1 | MORPHOLINE DOPAMINE AGONISTS FOR THE TREATMENT OF PAIN | PFIZER INC. | 2009-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318451-A1 | MORPHOLINE DOPAMINE AGONISTS FOR THE TREATMENT OF PAIN | OPRL1, OPRD1, OPRK1 | DRD3 26/4885DRD2 13/4885DRD1 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.