SCHEMBL441908

SCHEMBL441908

CC/C=[C]\C1CCCCC1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.32
ADH1C P00326 1/20 0.31
ADH1A P07327 1/20 0.31
CYP1A2 P05177 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2240665 0.97
SCHEMBL962970 0.92
SCHEMBL6159120 0.87
SCHEMBL2301260 0.81 CYP1A2 (0.33) SHBGADH1ACYP1A2
SCHEMBL2301258 0.81 CYP1A2 (0.33) SHBGADH1ACYP1A2
SCHEMBL6033218 0.78 CYP1A2 (0.30) CYP1A2
SCHEMBL6956347 0.78 CYP1A2 (0.40) CYP1A2
SCHEMBL2303897 0.78 CYP1A2 (0.40) CYP1A2
SCHEMBL2303911 0.75
SCHEMBL6964611 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 588 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1599464-B1 NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS AVENTIS PHARMA SA (FR) 2010-09-22 EP claimed
US-20070249710-A1 Biaromatic compounds and cosmetic/pharmaceutical applications thereof GALDERMA RESEARCH & DEVELOPMENT (FR) 2007-10-25 US claimed
US-20240199623-A1 SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINES AS CFTR MODULATORS ILDONG PHARMACEUTICAL CO., LTD. (KR) 2024-06-20 US disclosed
US-20240166593-A1 LIPIDS SUITABLE FOR NUCLEIC ACID DELIVERY RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2024-05-23 US disclosed
EP-4370106-A1 CANNABIDIOLIC ACID ESTERS FOR TREATING PRADER-WILLI SYNDROME EPM (IP), Inc. (US) 2024-05-22 EP disclosed
US-11970493-B2 Autotaxin inhibitor compounds ILDONG PHARMACEUTICAL CO., LTD. (KR) 2024-04-30 US disclosed
CN-117813081-A Cannabidiol esters for the treatment of Prader-Willi syndrome EPM(IP)公司 2024-04-02 CN disclosed
WO-2024003906-A1 CANNABINOID DERIVATIVES AND COMPOSITIONS COMPRISING SAME CANNASOUL ANALYTICS LTD. (IL) 2024-01-04 WO disclosed
US-11851389-B2 Cationic lipids for nucleic acid delivery and preparation thereof RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2023-12-26 US disclosed
WO-2023244059-A1 METHODS OF TREATING CANCER USING DUAL ANDROGEN RECEPTOR AND PDE5 INHIBITOR COMPOUNDS ILDONG PHARMACEUTICAL CO., LTD. (KR) 2023-12-21 WO disclosed
EP-4288104-A1 LIPIDS SUITABLE FOR NUCLEIC ACID DELIVERY Ramot at Tel-Aviv University Ltd. (IL) 2023-12-13 EP disclosed
WO-1998054158-A1 QUINOLINE AND QUINOXALINE COMPOUNDS WHICH INHIBIT PLATELET-DERIVED GROWTH FACTOR AND/OR p56lck TYROSINE KINASES RHÔNE-POULENC RORER PHARMACEUTICALS INC. (US) 1998-12-03 WO disclosed
WO-1998054157-A1 QUINOLINE AND QUINOXALINE COMPOUNDS WHICH INHIBIT PLATELET-DERIVED GROWTH FACTOR AND/OR p561ck TYROSINE KINASES RHÔNE-POULENC RORER PHARMACEUTICALS INC. (US) 1998-12-03 WO disclosed
WO-1998051324-A1 PEPTIDE PARATHYROID HORMONE ANALOGS RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1998-11-19 WO disclosed
EP-0871439-A1 SUBSTITUTED (ARYL, HETEROARYL, ARYLMETHYL OR HETEROARYLMETHYL) HYDROXAMIC ACID COMPOUNDS RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) 1998-10-21 EP disclosed
WO-1998032734-A1 SUBSTITUTED β-THIOCARBOXYLIC ACIDS RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1998-07-30 WO disclosed
WO-1998029376-A1 PROCESS FOR THE SOLID PHASE SYNTHESIS OF ALDEHYDES, KETONES, OXIMES, AMINES AND HYDROXAMIC ACID COMPOUNDS RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1998-07-09 WO disclosed
US-5750540-A SIDE EFFECT REDUCTION BANYU PHARMACEUTICAL CO., LTD. (JP) 1998-05-12 US disclosed
EP-0823423-A1 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES BANYU PHARMACEUTICAL CO., LTD. (JP) 1998-02-11 EP disclosed
WO-1997024117-A1 SUBSTITUTED (ARYL, HETEROARYL, ARYLMETHYL OR HETEROARYLMETHYL) HYDROXAMIC ACID COMPOUNDS RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1997-07-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11851389-B2 Cationic lipids for nucleic acid delivery and preparation thereof NPC1L1, NPC1, CETP SHBG 4849/4885ADH1C 3192/4885ADH1A 4103/4885
US-20240199623-A1 SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINES AS CFTR MODULATORS PDE4A, PDE4B, PDE6C SHBG 4220/4885ADH1C 3511/4885ADH1A 3520/4885
US-20240166593-A1 LIPIDS SUITABLE FOR NUCLEIC ACID DELIVERY NPC1L1, NPC1, FASN SHBG 4850/4885ADH1C 2535/4885ADH1A 3192/4885
US-11970493-B2 Autotaxin inhibitor compounds ENPP2, ATXN10, ATXN2L SHBG 1767/4885ADH1C 4661/4885ADH1A 4761/4885
US-20070249710-A1 Biaromatic compounds and cosmetic/pharmaceutical applications thereof RARG, RARA, RARB SHBG 518/4885ADH1C 893/4885ADH1A 316/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.