SCHEMBL4419490

SCHEMBL4419490

CCCCCCCCCCCC(Cl)[SiH](C)C

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.41
DNM1 Q05193 2/20 0.40
TSHR P16473 2/20 0.40
THRB P10828 1/20 0.40
OPRM1 P35372 1/20 0.39
ALDH1A1 P00352 1/20 0.38
GPR84 Q9NQS5 3/20 0.37
FDPS P14324 3/20 0.37
SPHK1 Q9NYA1 1/20 0.37
FFAR1 O14842 1/20 0.37
MAPT P10636 1/20 0.35
LCK P06239 1/20 0.35
PPARD Q03181 1/20 0.35
ZDHHC20 Q5W0Z9 1/20 0.35
ZDHHC2 Q9UIJ5 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1535409 1.00 LMNA (0.41) LMNADNM1TSHRTHRBOPRM1
SCHEMBL3794719 1.00 LMNA (0.41) LMNADNM1TSHRTHRBOPRM1
SCHEMBL17076505 1.00 LMNA (0.41) LMNADNM1TSHRTHRBOPRM1
SCHEMBL4944724 1.00 LMNA (0.41) LMNADNM1TSHRTHRBOPRM1
SCHEMBL1535401 1.00 LMNA (0.41) LMNADNM1TSHRTHRBOPRM1
SCHEMBL4062638 0.97 OPRM1 (0.40) LMNADNM1TSHRTHRBOPRM1
SCHEMBL9722866 0.90
SCHEMBL5574675 0.80 LMNA (0.41) LMNADNM1TSHRTHRBOPRM1
SCHEMBL5574691 0.80 LMNA (0.41) LMNADNM1TSHRTHRBOPRM1
SCHEMBL1535422 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4310138-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE THEREOF Techno-UMG Co., Ltd. (JP) 2024-01-24 EP disclosed
US-20230391987-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE THEREOF TECHNO-UMG CO., LTD. (JP) 2023-12-07 US disclosed
WO-2022195973-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE THEREOF テクノUMG株式会社 2022-09-22 WO disclosed
US-7498293-B2 Alkylaminosiloxanes as corrosion inhibitors CIBA SPECIALTY CHEMICALS CORP. (US) 2009-03-03 US disclosed
US-20050176596-A1 Alkylaminosiloxanes as corrosion inhibitors CIBA SPECIALTY CHEMICAL CORP. 2005-08-11 US disclosed
EP-1509534-A2 ALKYLAMINOSILOXANES AS CORROSION INHIBITORS Ciba SC Holding AG (CH) 2005-03-02 EP disclosed
WO-2003101947-A2 ALKYLAMINOSILOXANES AS CORROSION INHIBITORS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-12-11 WO disclosed