SCHEMBL4419665

SCHEMBL4419665

NNC(=O)CCn1ccc(=O)n(CCC(=O)NN)c1=O

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.38
MAPT P10636 2/20 0.38
PSMB1 P20618 1/20 0.38
KDM4E B2RXH2 1/20 0.38
LMNA P02545 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
DUT P33316 1/20 0.35
CYP2D6 P10635 2/20 0.34
CYP2C19 P33261 2/20 0.34
CYP2C9 P11712 1/20 0.34
ALOX15 P16050 1/20 0.34
GRIK3 Q13003 1/20 0.34
HSD17B10 Q99714 1/20 0.34
MEN1 O00255 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
POLB P06746 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4415628 0.81 MAPT (0.44) KMT2AMAPTPSMB1KDM4ELMNA
SCHEMBL808457 0.75 MAPT (0.48) KMT2AMAPTKDM4ELMNAL3MBTL1
SCHEMBL9125228 0.69 RXFP1 (0.44) MAPTLMNADUTCYP2D6CYP2C19
SCHEMBL12881193 0.69 LMNA (0.69) KMT2AMAPTKDM4ELMNACYP2C19
SCHEMBL4488844 0.68 KDM4E (0.39) KMT2AMAPTKDM4ELMNAMEN1
SCHEMBL26980355 0.68 APEX1 (0.61) KMT2AMAPTKDM4ELMNAL3MBTL1
SCHEMBL7274815 0.67 PDE4A (0.39) HSD17B10CYP1A2CYP3A4
SCHEMBL5310921 0.67 PRKCA (0.38) KMT2AMAPTCYP2D6CYP2C19CYP2C9
SCHEMBL16156819 0.66 HDAC6 (0.73) KMT2AMAPTKDM4ELMNACYP2D6
SCHEMBL26980311 0.65 KDM4E (0.41) KMT2AMAPTKDM4ELMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7638565-B2 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2009-12-29 US disclosed
US-20070054998-A1 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2007-03-08 US disclosed
EP-1686156-A1 POLYACETAL RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2006-08-02 EP disclosed