Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | KLK1 | P06870 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4418313 | 0.82 | ALDH1A1 (0.35) | ALDH1A1CYP3A4 | |
| SCHEMBL4419771 | 0.74 | PTGDR2 (0.36) | — | |
| SCHEMBL3165002 | 0.68 | PDCD1 (0.37) | ALDH1A1 | |
| SCHEMBL12678733 | 0.66 | POLB (0.38) | ALDH1A1CYP3A4 | |
| SCHEMBL4415025 | 0.58 | KMT2A (0.39) | ALDH1A1 | |
| SCHEMBL16493596 | 0.58 | NOTUM (0.37) | ALDH1A1CYP3A4 | |
| SCHEMBL4496878 | 0.57 | NOTUM (0.55) | ALDH1A1CYP3A4 | |
| SCHEMBL4421324 | 0.56 | OXER1 (0.41) | ALDH1A1 | |
| SCHEMBL4266779 | 0.56 | MTNR1A (0.37) | ALDH1A1CYP3A4 | |
| SCHEMBL4418839 | 0.56 | PREP (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2094662-A1 | POLYCYCLIC ACID COMPOUNDS USEFUL AS CRTH2 ANTAGONISTS AND ANTIALLERGIC AGENTS | Astellas Pharma Inc. (JP) | 2009-09-02 | — | — | EP | disclosed |
| WO-2008072784-A1 | POLYCYCLIC ACID COMPOUNDS USEFUL AS CRTH2 ANTAGONISTS AND ANTIALLERGIC AGENTS | ASTELLAS PHARMA INC. (JP) | 2008-06-19 | — | — | WO | disclosed |