Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.59 |
| ▸ | MAOA | P21397 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | AOC3 | Q16853 | 6/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4423740 | 0.92 | ITGB3 (0.56) | ITGB3ITGA2BMAOAMAOBAOC3 | |
| SCHEMBL4423694 | 0.88 | ITGB3 (0.76) | ITGB3ITGA2BMAOAMAOB | |
| SCHEMBL4418997 | 0.84 | ITGB3 (0.59) | ITGB3ITGA2BMAOAMAOBAOC3 | |
| SCHEMBL4418712 | 0.82 | ITGB3 (0.60) | ITGB3ITGA2BMAOAMAOBAOC3 | |
| SCHEMBL7028544 | 0.82 | EPHX2 (0.48) | ITGB3ITGA2BAOC3HRH3 | |
| SCHEMBL4419593 | 0.82 | ITGB3 (0.72) | ITGB3ITGA2BMAOAMAOBHRH3 | |
| SCHEMBL4418240 | 0.81 | S1PR1 (0.56) | ITGB3ITGA2BMAOAMAOB | |
| SCHEMBL4424269 | 0.81 | ITGB3 (0.61) | ITGB3ITGA2BMAOAMAOBAOC3 | |
| SCHEMBL3648103 | 0.81 | MAOB (0.60) | ITGB3ITGA2BMAOAMAOBAOC3 | |
| SCHEMBL4427043 | 0.80 | ITGB3 (0.62) | ITGB3ITGA2BMAOAMAOBAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501804-B1 | ISOQUINOLINE DERIVATIVES MAO-B INHIBITORS | HOFFMANN LA ROCHE (CH) | 2009-08-26 | — | — | EP | claimed |