Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD5 | P21918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4419892 | 0.82 | ITGB3 (0.59) | ITGB3ITGA2BAOC3HRH3 | |
| SCHEMBL7028538 | 0.82 | ITGB3 (0.41) | DRD2DRD3ITGB3ITGA2BAOC3 | |
| SCHEMBL4423740 | 0.75 | ITGB3 (0.56) | ITGB3ITGA2BAOC3HRH3 | |
| SCHEMBL20657110 | 0.74 | ALDH1A1 (0.61) | DRD2ITGB3ITGA2BMEN1ALDH1A1 | |
| SCHEMBL25362979 | 0.73 | AOC3 (0.48) | ITGB3ITGA2BAOC3 | |
| SCHEMBL30530638 | 0.73 | AOC3 (0.48) | ITGB3ITGA2BAOC3 | |
| SCHEMBL29677014 | 0.70 | MAPK1 (0.46) | DRD2DRD3ITGB3ITGA2BAOC3 | |
| SCHEMBL8379044 | 0.70 | ROCK2 (0.45) | ROCK2ROCK1 | |
| SCHEMBL7300982 | 0.70 | KDM4E (0.55) | DRD2DRD3ROCK2ITGB3ITGA2B | |
| SCHEMBL8347050 | 0.70 | ROCK2 (0.49) | EPHX2TP53DRD2DRD3ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030135045-A1 | Glycoprotein IIb/IIIa antagonists | FISHER MATTHEW J (US) | 2003-07-17 | — | — | US | disclosed |
| US-6472405-B1 | Glycoprotein IIB/IIIA antagonists | ELI LILLY AND COMPANY | 2002-10-29 | — | — | US | disclosed |
| EP-0635492-B1 | Glycoprotein IIb/IIIa antagonists | LILLY CO ELI (US) | 2002-10-02 | — | — | EP | disclosed |
| US-6137002-A | USEFUL FOR PREVENTION OF THROMBOSIS; FOR TREATING ATHEROSCLEROSIS AND ARTERIOSCLEROSIS, ACUTE MYOCARDIAL INFARCTION, CHRONIC STABLE ANGINA, UNSTABLE ANGINA, TRANSIENT ISCHEMIC ATTACKS AND STROKES, PERIPHERAL VASCULAR DISEASE, | ELI LILLY AND COMPANY (US) | 2000-10-24 | — | — | US | disclosed |
| US-5618843-A | INHIBIT PLATELET AGGREGATION | ELI LILLY AND COMPANY (US) | 1997-04-08 | — | — | US | disclosed |
| EP-0635492-A1 | Glycoprotein IIb/IIIa antagonists | ELI LILLY AND COMPANY (US) | 1995-01-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030135045-A1 | Glycoprotein IIb/IIIa antagonists | GP6, TBXA2R, ITGA2B | EPHX2 2213/4885TP53 832/4885DRD2 890/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.