Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 5/20 | 0.48 |
| ▸ | CA2 | P00918 | 5/20 | 0.48 |
| ▸ | CA4 | P22748 | 5/20 | 0.48 |
| ▸ | CA6 | P23280 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 2/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | NOS2 | P35228 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2690321 | 1.00 | KMT2A (0.52) | KMT2ACA1CA2CA4CA6 | |
| SCHEMBL7704612 | 1.00 | KMT2A (0.52) | KMT2ACA1CA2CA4CA6 | |
| SCHEMBL2691839 | 1.00 | KMT2A (0.52) | KMT2ACA1CA2CA4CA6 | |
| SCHEMBL3878315 | 1.00 | KMT2A (0.52) | KMT2ACA1CA2CA4CA6 | |
| SCHEMBL27081209 | 1.00 | KMT2A (0.52) | KMT2ACA1CA2CA4CA6 | |
| SCHEMBL11300049 | 1.00 | KMT2A (0.52) | KMT2ACA1CA2CA4CA6 | |
| SCHEMBL200410 | 0.98 | — | — | |
| Cyclohexanone SCHEMBL4581972 | 0.94 | KMT2A (0.47) | KMT2ACA1CA2CA4CA6 | |
| Methylene Chloride SCHEMBL28137470 | 0.91 | CA1 (0.45) | KMT2ACA1CA2CA4CA6 | |
| SCHEMBL21006006 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362023-B1 | METHOD FOR PRODUCING MACROCYCLIC KETONES | GIVAUDAN SA (CH) | 2009-04-15 | — | — | EP | disclosed |
| US-6951964-B2 | Method for producing macrocyclic ketones | GIVAUDAN SA (CH) | 2005-10-04 | — | — | US | disclosed |
| US-20040082816-A1 | Method for producting macrocyclic ketones | GIVAUDAN SA (CH) | 2004-04-29 | — | — | US | disclosed |
| EP-1362023-A1 | METHOD FOR PRODUCING MACROCYCLIC KETONES | Givaudan SA (CH) | 2003-11-19 | — | — | EP | disclosed |
| WO-2002068372-A1 | METHOD FOR PRODUCING MACROCYCLIC KETONES | GIVAUDAN SA (CH) | 2002-09-06 | — | — | WO | disclosed |
| EP-1236707-A1 | Process for the preparation of macrocyclic ketones | Givaudan SA (CH) | 2002-09-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082816-A1 | Method for producting macrocyclic ketones | ADH1C, ADH1A, AKR1C3 | KMT2A 3232/4885CA1 1351/4885CA2 3123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.