Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.44 |
| ▸ | FDPS | P14324 | 11/20 | 0.41 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.38 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6282200 | 0.88 | FDPS (0.47) | SMPD1FDPSGGPS1LPAR3LPAR1 | |
| SCHEMBL215087 | 0.84 | SMPD1 (0.55) | SMPD1FDPSGGPS1LPAR3LPAR1 | |
| SCHEMBL6282280 | 0.82 | SMPD1 (0.53) | SMPD1FDPSGGPS1LPAR3LPAR1 | |
| SCHEMBL3813551 | 0.81 | SMPD1 (0.56) | SMPD1FDPSGGPS1LPAR3LPAR1 | |
| SCHEMBL3814855 | 0.81 | SMPD1 (0.56) | SMPD1FDPSGGPS1LPAR3LPAR1 | |
| SCHEMBL28587117 | 0.81 | BTN3A1 (0.40) | SMPD1FDPSBTN3A1 | |
| SCHEMBL7168476 | 0.81 | SMPD1 (0.45) | SMPD1FDPSGGPS1LPAR3LPAR1 | |
| SCHEMBL28766325 | 0.80 | BTN3A1 (0.42) | SMPD1FDPSBTN3A1LPAR3LPAR1 | |
| SCHEMBL5459837 | 0.79 | FDPS (0.47) | SMPD1FDPSGGPS1LPAR3LPAR1 | |
| SCHEMBL2150670 | 0.79 | SMPD1 (0.63) | SMPD1FDPSGGPS1LPAR3LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150167041-A1 | ASTAXANTHIN PRODUCTION USING A RECOMBINANT MICROBIAL HOST CELL | E. I. DU PONT DE NEMOURS AND COMPANY | 2015-06-18 | — | — | US | disclosed |
| US-8846374-B2 | Carotenoid production in a recombinant oleaginous yeast | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-09-30 | — | — | US | disclosed |
| US-8815567-B2 | Coenzyme Q10 production in a recombinant oleaginous yeast | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-08-26 | — | — | US | disclosed |
| US-20120142082-A1 | CAROTENOID PRODUCTION IN A RECOMBINANT OLEAGINOUS YEAST | E. I. DU PONT DE NEMOURS AND COMPANY | 2012-06-07 | — | — | US | disclosed |
| US-20090142322-A1 | Coenzyme Q10 Production in a Recombinant Oleaginous Yeast | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-06-04 | — | — | US | disclosed |
| WO-2008073367-A1 | CAROTENOID PRODUCTION IN A RECOMBINANT OLEAGINOUS YEAST | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-06-19 | — | — | WO | disclosed |
| EP-1543115-B1 | SQUALENE SYNTHASE (SQS) GENE | DSM IP ASSETS BV (NL) | 2008-05-07 | — | — | EP | disclosed |
| US-7351564-B2 | SQS gene | DSM IP ASSETS B.V. (NL) | 2008-04-01 | — | — | US | disclosed |
| US-20060160172-A1 | Gene useful in a process to increase the microbial production of carotenoids | DSM IP ASSETS B.V. (NL) | 2006-07-20 | — | — | US | disclosed |
| US-6872556-B2 | Isoprenoid production | DSM IP ASSETS B.V. (NL) | 2005-03-29 | — | — | US | disclosed |
| US-20030190734-A1 | Isoprenoid production | ROCHE VITAMINS, INC. | 2003-10-09 | — | — | US | disclosed |
| US-6586202-B2 | Isolated DNA sequence encoding an enzyme in the mevalonate pathway or the pathway from isopentenyl pyrophosphate to farnesyl pyrophosphate. Vectors and plasmids including such DNA are also set forth. The invention also includes host | ROCHE VITAMINS, INC. | 2003-07-01 | — | — | US | disclosed |
| US-20030054523-A1 | Isoprenoid production | ROCHE VITAMINS INC. | 2003-03-20 | — | — | US | disclosed |
| US-6284506-B1 | MOLECULAR HYBRIDIZATION; CAROTENOID AND ASTAXANTHIN PRODUCTION; GENE EXPRESSION OF MELAVONATE OR ISOPENTENYL TO FARNESYL PYROPHOSPHATE BIOSYNTHETIC ENZYMES | ROCHE VITAMINS INC. | 2001-09-04 | — | — | US | disclosed |
| EP-0955363-A2 | Dna sequences encoding enzymes involved in production of isoprenoids | F. HOFFMANN-LA ROCHE AG (CH) | 1999-11-10 | — | — | EP | disclosed |