Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1376604 | 0.91 | CCR2 (0.53) | CCR2KCNH2 | |
| SCHEMBL4332074 | 0.79 | CCR2 (0.82) | CCR2KCNH2 | |
| SCHEMBL13612980 | 0.79 | CCR2 (0.82) | CCR2KCNH2 | |
| SCHEMBL744875 | 0.77 | CCR2 (0.76) | CCR2KCNH2 | |
| SCHEMBL1379551 | 0.75 | CCR2 (0.48) | CCR2KCNH2 | |
| SCHEMBL5319253 | 0.74 | CCR2 (0.50) | CCR2KCNH2 | |
| SCHEMBL5323144 | 0.73 | CCR2 (0.48) | CCR2KCNH2 | |
| SCHEMBL5235139 | 0.72 | CCR2 (0.50) | CCR2KCNH2 | |
| SCHEMBL5233880 | 0.72 | CCR2 (0.52) | CCR2KCNH2 | |
| SCHEMBL1380862 | 0.72 | CCR2 (0.39) | CCR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1696919-A4 | 3-CYCLOALKYLAMINOPYRROLIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTORS | INCYTE CORP (US) | 2009-07-01 | — | — | EP | disclosed |
| EP-1696919-A2 | 3-CYCLOALKYLAMINOPYRROLIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTORS | Incyte Corporation (US) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005060665-A2 | 3-CYCLOALKYLAMINOPYRROLIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTORS | INCYTE CORPORATION (US) | 2005-07-07 | — | — | WO | disclosed |