Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 7/20 | 0.63 |
| ▸ | CNR2 | P34972 | 6/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 4/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13602727 | 0.85 | CNR1 (0.84) | CNR1CNR2CRHR1CHRM1 | |
| SCHEMBL4367945 | 0.83 | CNR1 (0.49) | CNR1CNR2TSHR | |
| SCHEMBL4370563 | 0.83 | CNR1 (0.49) | CNR1CNR2TSHR | |
| SCHEMBL4380229 | 0.83 | CNR1 (0.49) | CNR1CNR2TSHR | |
| SCHEMBL4423703 | 0.83 | CNR1 (0.50) | CNR1CNR2PTGER1KCNH2NLRP3 | |
| SCHEMBL4380007 | 0.83 | CNR1 (0.60) | CNR1CNR2CRHR1TSHR | |
| SCHEMBL4371410 | 0.81 | CNR1 (0.48) | CNR1CNR2KCNH2NLRP3CHRM1 | |
| SCHEMBL4373566 | 0.81 | CNR1 (0.58) | CNR1CNR2CRHR1CHRM1TSHR | |
| SCHEMBL4367963 | 0.80 | CNR1 (0.47) | CNR1CNR2KCNH2NLRP3CRHR1 | |
| SCHEMBL4371549 | 0.80 | CNR1 (0.57) | CNR1CNR2CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583742-B1 | CB 1 RECEPTOUR INVERSE AGONISTS | HOFFMANN LA ROCHE (CH) | 2009-12-02 | — | — | EP | claimed |