Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 6/20 | 0.47 |
| ▸ | CNR2 | P34972 | 7/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4371549 | 0.92 | CNR1 (0.57) | CNR1CNR2HCRTR2TRPV1CRHR1 | |
| SCHEMBL4372987 | 0.91 | CNR1 (0.39) | CNR1CNR2TSHRKDM4EALDH1A1 | |
| SCHEMBL4370563 | 0.88 | CNR1 (0.49) | CNR1CNR2TSHR | |
| SCHEMBL4367945 | 0.88 | CNR1 (0.49) | CNR1CNR2TSHR | |
| SCHEMBL4369770 | 0.83 | CNR1 (0.48) | CNR1CRHR1 | |
| SCHEMBL4420518 | 0.80 | CNR1 (0.63) | CNR1CNR2TSHRCHRM1KCNH2 | |
| SCHEMBL4380229 | 0.80 | CNR1 (0.49) | CNR1CNR2TSHRKDM4EALDH1A1 | |
| SCHEMBL4371410 | 0.80 | CNR1 (0.48) | CNR1CNR2TSHRCHRM1KCNH2 | |
| SCHEMBL4423581 | 0.80 | CNR1 (0.46) | CNR1 | |
| SCHEMBL4380007 | 0.79 | CNR1 (0.60) | CNR1CNR2TSHRKDM4ETRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1749002-B1 | PYRROLE OR IMIDAZOLE AMIDES FOR TREATING OBESITY | HOFFMANN LA ROCHE (CH) | 2009-05-27 | — | — | EP | claimed |