Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 6/20 | 0.50 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4380229 | 0.86 | CNR1 (0.49) | CNR1CNR2 | |
| SCHEMBL13717371 | 0.86 | CNR1 (0.67) | CNR1CNR2TRPV1CHRM1TRPV4 | |
| SCHEMBL4371410 | 0.84 | CNR1 (0.48) | CNR1CNR2KCNH2NLRP3TRPV1 | |
| SCHEMBL4420518 | 0.83 | CNR1 (0.63) | CNR1CNR2KCNH2NLRP3CHRM1 | |
| SCHEMBL4370563 | 0.78 | CNR1 (0.49) | CNR1CNR2 | |
| SCHEMBL4367945 | 0.78 | CNR1 (0.49) | CNR1CNR2 | |
| SCHEMBL4380007 | 0.77 | CNR1 (0.60) | CNR1CNR2TRPV1CRHR1 | |
| SCHEMBL13717174 | 0.77 | CNR1 (0.81) | CNR1CNR2TRPV1CRHR1 | |
| SCHEMBL3929874 | 0.76 | CNR1 (0.54) | CNR1TRPV4CRHR1 | |
| SCHEMBL4375089 | 0.76 | CNR1 (0.39) | CNR1CHRM3TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583742-B1 | CB 1 RECEPTOUR INVERSE AGONISTS | HOFFMANN LA ROCHE (CH) | 2009-12-02 | — | — | EP | claimed |