Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2319479 | 1.00 | TSHR (0.48) | TSHRMAPTABCC4ALDH1A1TRPA1 | |
| SCHEMBL757068 | 0.88 | — | — | |
| SCHEMBL7526836 | 0.80 | TSHR (0.50) | TSHRMAPTABCC4ALDH1A1TRPA1 | |
| SCHEMBL14716699 | 0.80 | TSHR (0.50) | TSHRMAPTABCC4ALDH1A1TRPA1 | |
| SCHEMBL5527326 | 0.79 | TSHR (0.44) | TSHRMAPTABCC4ALDH1A1TRPA1 | |
| SCHEMBL28405823 | 0.79 | TSHR (0.50) | TSHRMAPTABCC4ALDH1A1TRPA1 | |
| SCHEMBL2118181 | 0.79 | TSHR (0.50) | TSHRMAPTABCC4ALDH1A1TRPA1 | |
| SCHEMBL11778637 | 0.79 | TSHR (0.44) | TSHRMAPTABCC4ALDH1A1TRPA1 | |
| SCHEMBL304895 | 0.79 | TSHR (0.50) | TSHRMAPTABCC4ALDH1A1TRPA1 | |
| SCHEMBL18186951 | 0.78 | TSHR (0.69) | TSHRMAPTABCC4ALDH1A1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498293-B2 | Alkylaminosiloxanes as corrosion inhibitors | CIBA SPECIALTY CHEMICALS CORP. (US) | 2009-03-03 | — | — | US | disclosed |
| US-7074906-B2 | Organic solvent-free process for the preparation of 2-(2-nitrophenylazo)phenols | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2006-07-11 | — | — | US | disclosed |
| US-20050176596-A1 | Alkylaminosiloxanes as corrosion inhibitors | CIBA SPECIALTY CHEMICAL CORP. | 2005-08-11 | — | — | US | disclosed |
| US-20050053562-A1 | Organic solvent-free process for the preparation of 2-(2-nitrophenylazo)phenols | CIBA SPECIALTY CHEMICALS CORP. | 2005-03-10 | — | — | US | disclosed |
| EP-1509534-A2 | ALKYLAMINOSILOXANES AS CORROSION INHIBITORS | Ciba SC Holding AG (CH) | 2005-03-02 | — | — | EP | disclosed |
| EP-1451254-A1 | ORGANIC SOLVENT-FREE PROCESS FOR THE PREPARATION OF 2-(2-NITROPHENYLAZO)PHENOLS | Ciba SC Holding AG (CH) | 2004-09-01 | — | — | EP | disclosed |
| EP-1144496-B1 | POLYMERIC STABILIZERS HAVING LOW POLYDISPERSITY | CIBA SC HOLDING AG (CH) | 2004-03-17 | — | — | EP | disclosed |
| WO-2003101947-A2 | ALKYLAMINOSILOXANES AS CORROSION INHIBITORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-12-11 | — | — | WO | disclosed |
| US-6583245-B1 | Ethylenically unsaturated compound (acrylate or acrylamide) having sterically hindered amine, hydroxyphenyl triazine, hydroxyphenylbenzotriazole or a o-hydroxy-benzophenone group; a nitroxyl free radical initiator | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-06-24 | — | — | US | disclosed |
| WO-2003048257-A1 | ORGANIC SOLVENT-FREE PROCESS FOR THE PREPARATION OF 2-(2-NITROPHENYLAZO)PHENOLS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-06-12 | — | — | WO | disclosed |
| EP-1144496-A1 | POLYMERIC STABILIZERS HAVING LOW POLYDISPERSITY | Ciba SC Holding AG (CH) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000039209-A1 | POLYMERIC STABILIZERS HAVING LOW POLYDISPERSITY | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-07-06 | — | — | WO | disclosed |
| US-6028129-A | Increasing the molecular weight of polycondensates and stabilizing them, using diepoxides of sterically hindered amines | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050053562-A1 | Organic solvent-free process for the preparation of 2-(2-nitrophenylazo)phenols | HPD, CYP8B1, CYP3A4 | TSHR 3835/4885MAPT 1347/4885ABCC4 1762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.