Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | APP | P05067 | 5/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | GSK3B | P49841 | 1/20 | 0.55 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.54 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.54 |
| ▸ | F3 | P13726 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6674756 | 1.00 | LMNA (0.68) | LMNASMN1; SMN2APPTDP1GSK3B | |
| SCHEMBL15611 | 1.00 | LMNA (0.68) | LMNASMN1; SMN2APPTDP1GSK3B | |
| SCHEMBL8872489 | 1.00 | LMNA (0.68) | LMNASMN1; SMN2APPTDP1GSK3B | |
| SCHEMBL4070148 | 1.00 | LMNA (0.68) | LMNASMN1; SMN2APPTDP1GSK3B | |
| SCHEMBL8872231 | 1.00 | LMNA (0.68) | LMNASMN1; SMN2APPTDP1GSK3B | |
| SCHEMBL4070152 | 1.00 | LMNA (0.68) | LMNASMN1; SMN2APPTDP1GSK3B | |
| SCHEMBL59457 | 1.00 | LMNA (0.68) | LMNASMN1; SMN2APPTDP1GSK3B | |
| SCHEMBL30746 | 1.00 | LMNA (0.68) | LMNASMN1; SMN2APPTDP1GSK3B | |
| SCHEMBL2489079 | 1.00 | LMNA (0.68) | LMNASMN1; SMN2APPTDP1GSK3B | |
| Hydrochloric Acid SCHEMBL10437237 | 0.99 | LMNA (0.70) | LMNASMN1; SMN2APPTDP1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10370657-B2 | Treatment of Collagen gene related diseases by inhibition of natural antisense transcript to a collagen gene | CURNA, INC. (US) | 2019-08-06 | — | — | US | disclosed |
| US-20170073680-A1 | TREATMENT OF COLLAGEN GENE RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO A COLLAGEN GENE | CURNA, INC. | 2017-03-16 | — | — | US | disclosed |
| EP-1187598-B1 | MICROPIGMENT MIXTURE | BASF SE (DE) | 2009-10-21 | — | — | EP | disclosed |