Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 6/20 | 0.33 |
| ▸ | THRA | P10827 | 5/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 6/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.30 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4413888 | 0.95 | RARA (0.33) | — | |
| SCHEMBL4415939 | 0.92 | FFAR1 (0.32) | — | |
| SCHEMBL13865611 | 0.89 | RARA (0.32) | — | |
| SCHEMBL13865551 | 0.87 | FFAR1 (0.34) | — | |
| SCHEMBL4422884 | 0.85 | FFAR1 (0.32) | — | |
| SCHEMBL13865605 | 0.84 | ALDH1A1 (0.30) | — | |
| SCHEMBL18965020 | 0.83 | FFAR1 (0.32) | — | |
| SCHEMBL13808398 | 0.83 | HDAC1 (0.30) | — | |
| SCHEMBL13808402 | 0.83 | HDAC1 (0.30) | — | |
| SCHEMBL14456310 | 0.82 | PTPN11 (0.36) | THRBTHRAPDK2PLA2G2DS1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658351-B1 | MESOGENIC COMPOUNDS, MEDIUM FOR ELECTRO-OPTICAL DISPLAYS AND ELECTRO-OPTICAL DISPLAY | MERCK PATENT GMBH (DE) | 2009-10-28 | — | — | EP | disclosed |
| EP-1658351-B1 | MESOGENIC COMPOUNDS, MEDIUM FOR ELECTRO-OPTICAL DISPLAYS AND ELECTRO-OPTICAL DISPLAY | MERCK PATENT GMBH (DE) | 2009-10-28 | — | — | EP | disclosed |
| US-7531106-B2 | Mesogenic compounds, medium for electro-optical displays and electro-optical display | MERCK PATENT GMBH (DE) | 2009-05-12 | — | — | US | disclosed |
| US-20060286308-A1 | Mesogenic compounds, medium for electro-optical displays and electro-optical display | MERCK PATENT GMBH (DE) | 2006-12-21 | — | — | US | disclosed |