Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | F10 | P00742 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PHGDH | O43175 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4415800 | 0.92 | ALDH1A1 (0.49) | FLT3HPGDTSHRF10L3MBTL1 | |
| SCHEMBL4417487 | 0.84 | F10 (0.49) | F10 | |
| SCHEMBL4419437 | 0.80 | F10 (0.47) | HPGDTSHRF10ALDH1A1MAPT | |
| SCHEMBL4414347 | 0.79 | F10 (0.43) | TSHRF10L3MBTL1ALDH1A1MAPT | |
| SCHEMBL4416638 | 0.77 | F10 (0.47) | F10 | |
| SCHEMBL4416019 | 0.76 | GRM5 (0.43) | TSHRF10ALDH1A1LMNAMEN1 | |
| SCHEMBL4422056 | 0.74 | F10 (0.48) | FLT3F10 | |
| SCHEMBL2781204 | 0.69 | ALDH1A1 (0.45) | TSHRF10L3MBTL1ALDH1A1MAPT | |
| SCHEMBL4414253 | 0.69 | SMN1; SMN2 (0.53) | TSHRF10L3MBTL1ALDH1A1NPC1 | |
| SCHEMBL4414413 | 0.68 | F10 (0.49) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1628972-B1 | INDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-04-22 | — | — | EP | claimed |