SCHEMBL4422080

SCHEMBL4422080

C=CC(NC(=O)CCCC(N)=O)C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.37
GNPAT O15228 1/20 0.36
KMT2A Q03164 3/20 0.34
BLM P54132 2/20 0.34
ALOX15 P16050 1/20 0.34
PMP22 Q01453 1/20 0.34
TSHR P16473 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
ALDH1A1 P00352 1/20 0.33
MEN1 O00255 2/20 0.32
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
CYP2D6 P10635 1/20 0.32
NFKB1 P19838 1/20 0.32
CYP2C19 P33261 1/20 0.32
ITGB3 P05106 2/20 0.32
ITGA2B P08514 2/20 0.32
SLC6A5 Q9Y345 3/20 0.32
FAAH O00519 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9335998 0.74 TSHR (0.33) KMT2ABLMTSHRALDH1A1MEN1
SCHEMBL3312141 0.72 TSHR (0.33) KMT2ABLMTSHRALDH1A1MEN1
SCHEMBL19369848 0.72 ITGB3 (0.41) MAPTGNPATKMT2ABLMALOX15
SCHEMBL7045847 0.70 NOD1 (0.56) GNPATKMT2ABLMALOX15PMP22
SCHEMBL21387151 0.70 GNPAT (0.57) GNPATKMT2ANOD1
SCHEMBL7046058 0.70 GNPAT (0.57) GNPATKMT2ANOD1
SCHEMBL9635608 0.69
SCHEMBL8815046 0.69 FOLH1 (0.33) KMT2ATSHRALDH1A1MEN1
SCHEMBL13368149 0.69 MEN1 (0.61) KMT2ATSHRSMN1; SMN2ALDH1A1MEN1
SCHEMBL10594684 0.69 MAPT (0.45) MAPTKMT2ATSHRSMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7638471-B2 Transparent cleansing bar comprising flipped N-acyl glutamate CONOPCO, INC., (US) 2009-12-29 US disclosed
WO-2009071299-A1 TRANSPARENT CLEANSING BAR UNILEVER PLC (GB) 2009-06-11 WO disclosed
US-20090149370-A1 Transparent Cleansing Bar CONOPCO, INC., D/B/A UNILEVER (US) 2009-06-11 US disclosed