SCHEMBL4422119

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4420246	0.93	HDAC1 (0.54)	HDAC1HDAC8HDAC3HDAC2HDAC6
	SCHEMBL4424883	0.88	HDAC8 (0.55)	HDAC1HDAC8HDAC2HDAC6ALDH1A1
	SCHEMBL4423968	0.82	KDM4E (0.60)	HDAC1HDAC8HDAC6ALDH1A1HPGD
	SCHEMBL5944236	0.80	HDAC1 (0.64)	HDAC1HDAC8HDAC3HDAC2HDAC6
	SCHEMBL8288789	0.79	DPP7 (0.48)	HDAC1ALDH1A1HPGDL3MBTL1
	SCHEMBL14449047	0.78	MMP13 (0.49)	HDAC6NPC1
	SCHEMBL8288792	0.78	ATR (0.47)	ALDH1A1HPGDNPC1L3MBTL1
	SCHEMBL14106943	0.75	ALDH1A1 (0.62)	HDAC1HDAC6HDAC4ALDH1A1HPGD
	SCHEMBL5456286	0.73	KDM4E (0.45)	HDAC1HDAC8HDAC3HDAC2HDAC6
	SCHEMBL5447915	0.73	HDAC1 (0.67)	HDAC1HDAC3HDAC2HDAC6ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.