Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4412893 | 0.92 | SPHK1 (0.47) | PTGS2SPHK1HDAC4SPHK2SMN1; SMN2 | |
| SCHEMBL13598277 | 0.87 | GPR119 (0.54) | PTGS2SPHK1HDAC4SPHK2 | |
| SCHEMBL4416567 | 0.81 | SPHK1 (0.42) | PTGS2SPHK1SPHK2SMN1; SMN2KCNH2 | |
| SCHEMBL4412979 | 0.81 | SPHK1 (0.42) | PTGS2SPHK1SPHK2SMN1; SMN2KCNH2 | |
| SCHEMBL4415854 | 0.81 | SPHK2 (0.55) | SPHK1HDAC4SPHK2MCHR1 | |
| SCHEMBL14640893 | 0.80 | SPHK1 (0.49) | PTGS2SPHK1HDAC4SPHK2SMN1; SMN2 | |
| SCHEMBL13598291 | 0.80 | GPR119 (0.55) | SPHK1HDAC4SPHK2SMN1; SMN2 | |
| SCHEMBL4412654 | 0.80 | GPR119 (0.40) | PTGS2SPHK1HDAC4SPHK2KCNH2 | |
| SCHEMBL4424803 | 0.80 | SPHK1 (0.46) | SPHK1HDAC4SPHK2SMN1; SMN2POLB | |
| SCHEMBL4424695 | 0.80 | SPHK2 (0.49) | SPHK1SPHK2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325924-A1 | GPCR Agonists | PROSIDION LIMITED (GB) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325924-A1 | GPCR Agonists | GPR119, GCGR, GPR27 | PTGS2 1870/4885SPHK1 686/4885HDAC4 2550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.