SCHEMBL4422764

SCHEMBL4422764

OC[C@H]1O[C@@H](n2ccc3c(NO)ncnc32)[C@H](O)[C@@H]1O

nearest known ligand 0.74

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ADK P55263 2/20 0.74
METTL3 Q86U44 1/20 0.66
METTL14 Q9HCE5 1/20 0.66
SLC29A1 Q99808 1/20 0.60
PRMT5 O14744 1/20 0.59
WDR77 Q9BQA1 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14075944 1.00 ADK (0.74) ADKMETTL3METTL14SLC29A1PRMT5
SCHEMBL31237241 1.00 ADK (0.74) ADKMETTL3METTL14SLC29A1PRMT5
SCHEMBL23982517 0.89 ADK (0.73) ADKMETTL3METTL14SLC29A1
SCHEMBL30047254 0.89 ADK (0.73) ADKMETTL3METTL14SLC29A1PRMT5
SCHEMBL30689918 0.89 ADK (0.73) ADKMETTL3METTL14SLC29A1
SCHEMBL20419319 0.89 ADK (0.73) ADKMETTL3METTL14SLC29A1
SCHEMBL17816362 0.89 ADK (0.73) ADKMETTL3METTL14SLC29A1
SCHEMBL20419313 0.89 ADK (0.73) ADKMETTL3METTL14SLC29A1
SCHEMBL15477884 0.85 METTL3 (0.79) ADKMETTL3METTL14SLC29A1
SCHEMBL15570446 0.85 METTL3 (0.79) ADKMETTL3METTL14SLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023152709-A1 RNA POLYMERASE INHIBITORS AND METHODS USING SAME ARBUTUS BIOPHARMA CORPORATION (CA) 2023-08-17 WO claimed
EP-4142744-A1 MESENCHYMAL STEM CELL THERAPIES Factor Bioscience Inc. (US) 2023-03-08 EP claimed
EP-1572097-A2 NUCLEOSIDE DERIVATIVES FOR TREATING HEPATITIS C VIRUS INFECTION GENELABS TECHNOLOGIES, INC. (US) 2005-09-14 EP claimed
US-20040147464-A1 Nucleoside derivatives for treating hepatitis C virus infection GENELABS TECHNOLOGIES, INC. 2004-07-29 US claimed
WO-2004028481-A2 NUCLEOSIDE DERIVATIVES FOR TREATING HEPATITIS C VIRUS INFECTION GENELABS TECHNOLOGIES, INC. (US) 2004-04-08 WO claimed
EP-4329783-A1 COMPOSITIONS AND METHODS RELATED TO MEGAKARYOCYTE-DERIVED EXTRACELLULAR VESICLES FOR FANCONI ANEMIA STRM.Bio Incorporated (US) 2024-03-06 EP disclosed
EP-4301848-A1 ENGINEERED IMMUNE CELL THERAPIES Factor Bioscience Inc. (US) 2024-01-10 EP disclosed
WO-2023205424-A2 LIPID COMPOSITIONS AND METHODS FOR NUCLEIC ACID DELIVERY GREENLIGHT BIOSCIENCES, INC. (US) 2023-10-26 WO disclosed
EP-4232005-A1 COMPOSITIONS AND METHODS RELATED TO MEGAKARYOCYTE-DERIVED EXTRACELLULAR VESICLES FOR TREATING MYELOPROLIFERATIVE NEOPLASMS STRM.Bio Incorporated (US) 2023-08-30 EP disclosed
WO-2023152709-A1 RNA POLYMERASE INHIBITORS AND METHODS USING SAME ARBUTUS BIOPHARMA CORPORATION (CA) 2023-08-17 WO disclosed
EP-4150054-A1 COMPOSITIONS AND METHODS RELATED TO MEGAKARYOCYTE-DERIVED EXTRACELLULAR VESICLES Sterm.Bio Incorporated (US) 2023-03-22 EP disclosed
EP-4142744-A1 MESENCHYMAL STEM CELL THERAPIES Factor Bioscience Inc. (US) 2023-03-08 EP disclosed
WO-2022187704-A1 ENGINEERED IMMUNE CELL THERAPIES FACTOR BIOSCIENCE INC. (US) 2022-09-09 WO disclosed
WO-2022087505-A1 COMPOSITIONS AND METHODS RELATED TO MEGAKARYOCYTE-DERIVED EXTRACELLULAR VESICLES FOR TREATING MYELOPROLIFERATIVE NEOPLASMS STRM.BIO INCORPORATED (US) 2022-04-28 WO disclosed
US-7629320-B2 Nucleoside derivatives for treating hepatitis C virus infection SMITHKLINE BEECHAM CORPORATION (US) 2009-12-08 US disclosed
US-20080249060-A1 NUCLEOSIDE DERIVATIVES FOR TREATING HEPATITIS C VIRUS INFECTION GENELABS TECHNOLOGIES, INC. 2008-10-09 US disclosed
US-7425547-B2 Nucleoside derivatives for treating hepatitis C virus infection GENELABS TECHNOLOGIES, INC. (US) 2008-09-16 US disclosed
EP-1572097-A2 NUCLEOSIDE DERIVATIVES FOR TREATING HEPATITIS C VIRUS INFECTION GENELABS TECHNOLOGIES, INC. (US) 2005-09-14 EP disclosed
US-20040147464-A1 Nucleoside derivatives for treating hepatitis C virus infection GENELABS TECHNOLOGIES, INC. 2004-07-29 US disclosed
WO-2004028481-A2 NUCLEOSIDE DERIVATIVES FOR TREATING HEPATITIS C VIRUS INFECTION GENELABS TECHNOLOGIES, INC. (US) 2004-04-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080249060-A1 NUCLEOSIDE DERIVATIVES FOR TREATING HEPATITIS C VIRUS INFECTION HAVCR2, PNP, NTPCR ADK 222/4885METTL3 587/4885METTL14 1882/4885
US-20040147464-A1 Nucleoside derivatives for treating hepatitis C virus infection HAVCR2, PNP, NTPCR ADK 222/4885METTL3 587/4885METTL14 1882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.