Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 4/20 | 0.59 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.54 |
| ▸ | ERN1 | O75460 | 3/20 | 0.50 |
| ▸ | INPPL1 | O15357 | 11/20 | 0.46 |
| ▸ | INPP5A | Q14642 | 6/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | INPP5B | P32019 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13322867 | 0.79 | PTGDR2 (0.47) | SRCPTGDR2ERN1 | |
| SCHEMBL4370189 | 0.78 | MAPK1 (0.54) | INPPL1INPP5AAKT1INPP5B | |
| SCHEMBL8388387 | 0.77 | SRC (0.56) | SRCERN1INPPL1INPP5AAKT1 | |
| SCHEMBL27746698 | 0.77 | MAPK1 (0.52) | INPPL1INPP5AAKT1INPP5B | |
| SCHEMBL1415050 | 0.76 | PTGDR2 (0.44) | SRCPTGDR2ERN1 | |
| SCHEMBL28441264 | 0.76 | PTGDR2 (0.57) | PTGDR2ERN1 | |
| SCHEMBL13343010 | 0.75 | INPPL1 (0.48) | INPPL1INPP5AAKT1INPP5B | |
| SCHEMBL9135651 | 0.74 | PTGDR2 (0.46) | SRCPTGDR2ERN1 | |
| SCHEMBL3514846 | 0.74 | SRC (1.00) | SRCPTGDR2ERN1INPPL1INPP5A | |
| SCHEMBL153974 | 0.74 | ERN1 (0.58) | PTGDR2ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009152171-A1 | CORTICOSTEROID LINKED BETA-AGONIST COMPOUNDS FOR USE IN THERAPY | GILEAD SCIENCES, INC. (US) | 2009-12-17 | — | — | WO | disclosed |