SCHEMBL8388387

SCHEMBL8388387

COc1ccc(OP(=O)(O)O)c(C=O)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 3/20 0.56
ERN1 O75460 3/20 0.56
ALDH1A1 P00352 3/20 0.53
TRIM24 O15164 1/20 0.51
TYR P14679 1/20 0.51
TRIM33 Q9UPN9 1/20 0.51
INPPL1 O15357 4/20 0.50
INPP5A Q14642 3/20 0.50
KDM4E B2RXH2 1/20 0.50
RAB9A P51151 1/20 0.50
JUN P05412 1/20 0.46
NFKB1 P19838 1/20 0.46
TUBB1 Q9H4B7 1/20 0.43
ABCG2 Q9UNQ0 1/20 0.43
AKT1 P31749 1/20 0.43
CYP1A2 P05177 2/20 0.42
CYP1A1 P04798 1/20 0.42
NFE2L2 Q16236 1/20 0.42
CYP1B1 Q16678 1/20 0.42
INPP5B P32019 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL172939 0.81 ALDH1A1 (0.71) ERN1ALDH1A1TRIM24TYRTRIM33
SCHEMBL29392394 0.81 ALDH1A1 (0.71) ERN1ALDH1A1TRIM24TYRTRIM33
SCHEMBL8518374 0.77 ERN1 (0.59) SRCERN1ALDH1A1TRIM24TYR
SCHEMBL7591800 0.77 ERN1 (0.59) ERN1ALDH1A1TRIM24TYRTRIM33
SCHEMBL4422950 0.77 SRC (0.59) SRCERN1INPPL1INPP5AAKT1
SCHEMBL16112011 0.77 ALDH1A1 (0.61) ERN1ALDH1A1TRIM24TYRTRIM33
SCHEMBL16045979 0.75 ALDH1A1 (0.59) ERN1ALDH1A1TRIM24TYRTRIM33
SCHEMBL31318321 0.75 INPPL1 (0.61) INPPL1INPP5AKDM4EAKT1INPP5B
SCHEMBL4644522 0.75 ALDH1A1 (0.59) ERN1ALDH1A1TRIM24TYRTRIM33
SCHEMBL28676135 0.75 ALDH1A1 (0.54) ERN1ALDH1A1TRIM24TYRTRIM33

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0487343-B1 Process for preparing a lithographic plate FUJI PHOTO FILM CO LTD (JP) 1999-04-28 EP disclosed
EP-0487343-A1 Process for preparing a lithographic plate Fuji Photo Film Co., Ltd. (JP) 1992-05-27 EP disclosed