Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGM | P11217 | 3/20 | 0.53 |
| ▸ | TK2 | O00142 | 4/20 | 0.50 |
| ▸ | P2RY6 | Q15077 | 7/20 | 0.47 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.46 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.46 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.46 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14929088 | 0.96 | PYGM (0.57) | PYGMTK2P2RY6SLC28A1SLC28A2 | |
| SCHEMBL14930959 | 0.96 | PYGM (0.57) | PYGMTK2P2RY6SLC28A1SLC28A2 | |
| SCHEMBL14853756 | 0.96 | PYGM (0.57) | PYGMTK2P2RY6SLC28A1SLC28A2 | |
| SCHEMBL546996 | 0.96 | PYGM (0.57) | PYGMTK2P2RY6SLC28A1SLC28A2 | |
| SCHEMBL14842287 | 0.96 | PYGM (0.57) | PYGMTK2P2RY6SLC28A1SLC28A2 | |
| SCHEMBL41703 | 0.93 | PYGM (0.61) | PYGMTK2P2RY6SLC28A1SLC28A2 | |
| SCHEMBL18512877 | 0.93 | PYGM (0.61) | PYGMTK2P2RY6SLC28A1SLC28A2 | |
| SCHEMBL18512878 | 0.93 | PYGM (0.61) | PYGMTK2P2RY6SLC28A1SLC28A2 | |
| SCHEMBL18161337 | 0.88 | PYGM (0.55) | PYGMTK2P2RY6SLC28A1SLC28A2 | |
| SCHEMBL18158974 | 0.88 | PYGM (0.55) | PYGMTK2P2RY6SLC28A1SLC28A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210244828-A1 | MIRI26-5P FOR TREATING MOTOR NEURON DISEASES | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2021-08-12 | — | — | US | disclosed |
| EP-3796919-A1 | MIR126-5P FOR TREATING MOTOR NEURON DISEASES | Ramot at Tel-Aviv University Ltd. (IL) | 2021-03-31 | — | — | EP | disclosed |
| WO-2020227777-A1 | METHOD FOR PROMOTING AUTOPHAGY | MONASH UNIVERSITY (AU) | 2020-11-19 | — | — | WO | disclosed |
| US-9179654-B2 | Inhibition of angiogenesis | CORNELL RESEARCH FOUNDATION, INC. (US) | 2015-11-10 | — | — | US | disclosed |
| US-9006195-B2 | Regulation of hematopoietic stem cell functions through microRNAs | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2015-04-14 | — | — | US | disclosed |
| WO-2013017542-A1 | METHOD FOR PREVENTING OR TREATING MEMORY IMPAIRMENT AND PHARMACEUTICAL COMPOSITIONS USEFUL THEREFOR | GEORG-AUGUST-UNIVERSITÄT GÖTTINGEN (DE) | 2013-02-07 | — | — | WO | disclosed |
| US-20130028956-A1 | METHOD FOR PREVENTING OR TREATING MEMORY IMPAIRMENT AND PHARMACEUTICAL COMPOSITIONS USEFUL THEREFORE | GEORG-AUGUST-UNIVERSITAET GOETTINGEN STIFTUNG OEFFENTLICHEN RECHTS UNIVERSITAETSMEDIZIN (DE) | 2013-01-31 | — | — | US | disclosed |
| WO-2012177565-A2 | REGULATION OF MACROPHAGE ACTIVATION USING MIR - 125B | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-12-27 | — | — | WO | disclosed |
| US-20120322854-A1 | REGULATION OF MACROPHAGE ACTIVATION USING MIR-125B | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-12-20 | — | — | US | disclosed |
| WO-2012037043-A2 | TREATMENT OF AUTOIMMUNE INFLAMMATION USING MIR-155 | CALIFORNIA INSTITUTE OF TECHNOLGOY (US) | 2012-03-22 | — | — | WO | disclosed |
| EP-1691817-A2 | NF-kB OLIGONUCLEOTIDE DECOY MOLECULES | Corgentech, Inc. (US) | 2006-08-23 | — | — | EP | disclosed |
| US-20060069055-A1 | Delivery of polynucleotides | ANESIVA, INC. | 2006-03-30 | — | — | US | disclosed |
| WO-2006034433-A2 | DELIVERY OF POLYNUCLEOTIDES | ANESIVA, INC. (US) | 2006-03-30 | — | — | WO | disclosed |
| US-20050215503-A1 | HIF oligonucleotide decoy molecules | ANESIVA, INC. | 2005-09-29 | — | — | US | disclosed |
| US-20050182012-A1 | NF-kappaB oligonucleotide decoy molecules | ANESIVA, INC. | 2005-08-18 | — | — | US | disclosed |
| US-20050164240-A1 | E2F oligonucleotide decoy molecules | CORGENTECH, INC. (US) | 2005-07-28 | — | — | US | disclosed |
| WO-2005056795-A2 | HIF OLIGONUCLEOTIDE DECOY MOLECULES | CORGENTECH, INC. (US) | 2005-06-23 | — | — | WO | disclosed |
| WO-2005056020-A2 | NF-KB OLIGONUCLEOTIDE DECOY MOLECULES | CORGENTECH, INC. (US) | 2005-06-23 | — | — | WO | disclosed |
| WO-2005035547-A2 | E2F OLIGONUCLEOTIDE DECOY MOLECULES | CORGENTECH, INC. (US) | 2005-04-21 | — | — | WO | disclosed |
| US-20040266712-A1 | Selective inhibition of vascular smooth muscle cell proliferation | MCEVOY LESLIE M (US) | 2004-12-30 | — | — | US | disclosed |