SCHEMBL546996

SCHEMBL546996

COC(=O)COc1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)[nH]c1=O

nearest known ligand 0.57

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PYGM P11217 3/20 0.57
TK2 O00142 4/20 0.53
P2RY6 Q15077 7/20 0.50
SLC28A1 O00337 1/20 0.49
SLC28A2 O43868 1/20 0.49
SLC29A1 Q99808 1/20 0.49
SLC28A3 Q9HAS3 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14853756 1.00 PYGM (0.57) PYGMTK2P2RY6SLC28A1SLC28A2
SCHEMBL14930959 1.00 PYGM (0.57) PYGMTK2P2RY6SLC28A1SLC28A2
SCHEMBL14842287 1.00 PYGM (0.57) PYGMTK2P2RY6SLC28A1SLC28A2
SCHEMBL14929088 1.00 PYGM (0.57) PYGMTK2P2RY6SLC28A1SLC28A2
SCHEMBL442314 0.96 PYGM (0.53) PYGMTK2P2RY6SLC28A1SLC28A2
SCHEMBL18161337 0.92 PYGM (0.55) PYGMTK2P2RY6SLC28A1SLC28A2
SCHEMBL18158974 0.92 PYGM (0.55) PYGMTK2P2RY6SLC28A1SLC28A2
SCHEMBL26370054 0.91 PYGM (0.47) PYGMTK2P2RY6
SCHEMBL29634965 0.91 TK2 (0.52) PYGMTK2
SCHEMBL18512878 0.88 PYGM (0.61) PYGMTK2P2RY6SLC28A1SLC28A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 731 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4705468-A1 MAMMALIAN POLYCISTRONIC EXPRESSION SYSTEM FOR DIRECT TRANSLATION FROM RNA AND SECRETION OF CARGO California Institute of Technology (US) 2026-03-11 EP claimed
WO-2024229296-A1 MAMMALIAN POLYCISTRONIC EXPRESSION SYSTEM FOR DIRECT TRANSLATION FROM RNA AND SECRETION OF CARGO CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2024-11-07 WO claimed
WO-2023217209-A1 DOUBLE-STRANDED RNA MOLECULE AND PHARMACEUTICAL USE THEREOF 澳门科技大学 2023-11-16 WO claimed
US-10441653-B2 Nucleic acid comprising GlXmGn as an immune-stimulating agent/adjuvant CUREVAC AG (DE) 2019-10-15 US claimed
EP-3394327-A1 DNA-ENCODED CHEMICAL LIBRARY, USE THEREOF AND METHOD TO SYNTHESIZE THE LIBRARY Technische Universität Dortmund (DE) 2018-10-31 EP claimed
WO-2017108741-A1 DNA-ENCODED CHEMICAL LIBRARY, USE THEREOF AND METHOD TO SYNTHESIZE THE LIBRARY TECHNISCHE UNIVERSITÄT DORTMUND (DE) 2017-06-29 WO claimed
EP-3184674-A1 DNA-ENCODED CHEMICAL LIBRARY, USE THEREOF AND METHOD TO SYNTHESIZE THE LIBRARY Technische Universität Dortmund (DE) 2017-06-28 EP claimed
EP-0795029-A1 CHEMICAL LABELLING OF OBJECTS Pabio (NO) 1997-09-17 EP claimed
WO-1996017954-A1 CHEMICAL LABELLING OF OBJECTS PABIO (DK) 1996-06-13 WO claimed
US-12637672-B2 Oligonucleotide compositions and methods thereof WAVE LIFE SCIENCES LTD. (SG) 2026-05-26 US disclosed
WO-2026102473-A1 TEMPERATURE DEPENDENT PROBES FOR TARGET DETECTION SPEEDX PTY LTD (AU) 2026-05-21 WO disclosed
EP-3827390-B1 SYSTEMS AND METHODS FOR SUPPORTING MULTIPLE AUTOMATED WORKFLOWS LIFEFOUNDRY INC (US) 2026-05-20 EP disclosed
CN-122031506-A Chiral control 波涛生命科学有限公司 2026-05-15 CN disclosed
EP-4731186-A2 METHODS AND COMPOSITIONS FOR TREATING EPITHELIAL DISEASES The Regents of the University of California (US) 2026-04-29 EP disclosed
WO-2000026226-A1 MULTIDOMAIN POLYNUCLEOTIDE MOLECULAR SENSORS YALE UNIVERSITY (US) 2000-05-11 WO disclosed
EP-0795029-A1 CHEMICAL LABELLING OF OBJECTS Pabio (NO) 1997-09-17 EP disclosed
WO-1996017954-A1 CHEMICAL LABELLING OF OBJECTS PABIO (DK) 1996-06-13 WO disclosed
EP-0311694-B1 NUCLEOSIDE DERIVATIVES AND PROCESS FOR THEIR PREPARATION RIKAGAKU KENKYUSHO (JP) 1995-12-13 EP disclosed
US-5144018-A Antiviral Agents RIKAGAKU KENKYUSHO (JP) 1992-09-01 US disclosed
EP-0311694-A1 NUCLEOSIDE DERIVATIVES AND PROCESS FOR THEIR PREPARATION RIKAGAKU KENKYUSHO (JP) 1989-04-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12637672-B2 Oligonucleotide compositions and methods thereof UPF1, SMN1; SMN2, RNGTT PYGM 15/4885TK2 313/4885P2RY6 362/4885
US-10441653-B2 Nucleic acid comprising GlXmGn as an immune-stimulating agent/adjuvant TLR9, TLR7, GMNN PYGM 983/4885TK2 1245/4885P2RY6 288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.