Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 14/20 | 0.54 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4423190 | 0.92 | GPR119 (0.55) | GPR119PRMT5GAATHRBSMN1; SMN2 | |
| SCHEMBL4422338 | 0.86 | GPR119 (0.54) | GPR119 | |
| SCHEMBL4423394 | 0.86 | GPR119 (0.54) | GPR119PRMT5WDR77HDAC4 | |
| SCHEMBL13598239 | 0.85 | GPR119 (0.54) | GPR119PRMT5DDB1CRBNWDR77 | |
| SCHEMBL4426132 | 0.84 | GPR119 (0.53) | GPR119 | |
| SCHEMBL4416064 | 0.84 | GPR119 (0.52) | GPR119PRMT5DDB1CRBNWDR77 | |
| SCHEMBL4415779 | 0.79 | GPR119 (0.50) | GPR119GAATHRBSMN1; SMN2HDAC4 | |
| SCHEMBL13598193 | 0.78 | GPR119 (0.54) | GPR119PRMT5WDR77HDAC4 | |
| SCHEMBL4420416 | 0.76 | GPR119 (0.53) | GPR119PRMT5WDR77HDAC4 | |
| SCHEMBL4563275 | 0.75 | GPR119 (0.52) | GPR119PRMT5WDR77HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325924-A1 | GPCR Agonists | PROSIDION LIMITED (GB) | 2009-12-31 | — | — | US | disclosed |
| US-20090325924-A1 | GPCR Agonists | PROSIDION LIMITED (GB) | 2009-12-31 | — | — | US | disclosed |
| US-20090325924-A1 | GPCR Agonists | PROSIDION LIMITED (GB) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325924-A1 | GPCR Agonists | GPR119, GCGR, GPR27 | GPR119 1/4885PRMT5 3682/4885GAA 1245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.