⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12925939 | 0.80 | LMNA (0.34) | — | |
| SCHEMBL10376639 | 0.72 | LMNA (0.50) | — | |
| SCHEMBL18721815 | 0.68 | CSNK2A1 (0.30) | — | |
| SCHEMBL14149209 | 0.68 | — | — | |
| SCHEMBL1143207 | 0.68 | IDO1 (0.41) | — | |
| SCHEMBL25250677 | 0.68 | — | — | |
| SCHEMBL6869641 | 0.67 | IDO1 (0.39) | — | |
| SCHEMBL15604418 | 0.65 | — | — | |
| SCHEMBL15980650 | 0.65 | — | — | |
| SCHEMBL2680443 | 0.64 | LMNA (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009155448-A1 | BIPHENYL SULFONAMIDES AS DUAL ANGIOTENSIN ENDOTHELIN RECEPTOR ANTAGONISTS | LIGAND PHARMACEUTICALS INC. (US) | 2009-12-23 | — | — | WO | disclosed |