Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1143207 | 0.97 | IDO1 (0.41) | IDO1HTTSMN1; SMN2TLR8LMNA | |
| SCHEMBL12925939 | 0.78 | LMNA (0.34) | IDO1HTTSMN1; SMN2LMNA | |
| SCHEMBL14165804 | 0.77 | HTT (0.35) | IDO1HTTSMN1; SMN2LMNA | |
| SCHEMBL19754271 | 0.77 | IDO1 (0.41) | IDO1HTTTLR8LMNA | |
| SCHEMBL29484711 | 0.77 | HTT (0.35) | IDO1HTTSMN1; SMN2LMNA | |
| SCHEMBL17342568 | 0.77 | TLR8 (0.44) | IDO1HTTSMN1; SMN2TLR8LMNA | |
| SCHEMBL12721102 | 0.73 | IDO1 (0.38) | IDO1TLR8LMNA | |
| SCHEMBL9682575 | 0.73 | IDO1 (0.38) | IDO1TLR8LMNA | |
| SCHEMBL2223659 | 0.72 | IDO1 (0.50) | IDO1HTTTLR8LMNA | |
| SCHEMBL10376639 | 0.70 | LMNA (0.50) | IDO1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091957-B1 | PYRIMIDIN-AMINOMETHYL-PYRIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN THE CONTROL OF HELICOBACTER BACTERIA | ALTANA PHARMA AG (DE) | 2004-12-15 | — | — | EP | disclosed |
| US-6395732-B1 | BACTERICIDES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2002-05-28 | — | — | US | disclosed |
| EP-1091957-A1 | PYRIMIDIN-AMINOMETHYL-PYRIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN THE CONTROL OF HELICOBACTER BACTERIA | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 2001-04-18 | — | — | EP | disclosed |
| WO-1999061439-A1 | PYRIMIDIN-AMINOMETHYL-PYRIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN THE CONTROL OF HELICOBACTER BACTERIA | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1999-12-02 | — | — | WO | disclosed |