Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 3/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4372521 | 0.86 | CNR1 (0.51) | CNR1TRPV4ACKR3 | |
| SCHEMBL4368598 | 0.85 | CNR2 (0.42) | CNR1 | |
| SCHEMBL4423581 | 0.82 | CNR1 (0.46) | CNR1FAAH | |
| SCHEMBL4372987 | 0.81 | CNR1 (0.39) | CNR1FAAHCHRM3ACKR3 | |
| SCHEMBL4374742 | 0.77 | TSHR (0.42) | CNR1FAAH | |
| SCHEMBL4375499 | 0.77 | CNR1 (0.49) | CNR1FAAH | |
| SCHEMBL4368758 | 0.76 | CNR1 (0.51) | CNR1FAAH | |
| SCHEMBL4423703 | 0.76 | CNR1 (0.50) | CNR1TRPV4CHRM3 | |
| SCHEMBL4367945 | 0.75 | CNR1 (0.49) | CNR1 | |
| SCHEMBL4370563 | 0.75 | CNR1 (0.49) | CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1749002-B1 | PYRROLE OR IMIDAZOLE AMIDES FOR TREATING OBESITY | HOFFMANN LA ROCHE (CH) | 2009-05-27 | — | — | EP | claimed |