Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LHCGR | P22888 | 7/20 | 0.48 |
| ▸ | FSHR | P23945 | 2/20 | 0.48 |
| ▸ | BRAF | P15056 | 11/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 3/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4421281 | 0.94 | LHCGR (0.50) | LHCGRFSHRBRAFTSHRPDE4A | |
| SCHEMBL4432274 | 0.93 | LHCGR (0.48) | LHCGRFSHRBRAFTSHRPDE4A | |
| SCHEMBL5037173 | 0.91 | LHCGR (0.62) | LHCGRFSHRTSHR | |
| SCHEMBL5034058 | 0.85 | LHCGR (0.63) | LHCGRFSHRTSHR | |
| SCHEMBL5036592 | 0.84 | LHCGR (0.61) | LHCGRFSHRTSHR | |
| SCHEMBL4431519 | 0.83 | LHCGR (0.53) | LHCGRFSHRBRAFTSHRPDE4A | |
| SCHEMBL4427689 | 0.82 | LHCGR (0.52) | LHCGRFSHRBRAFTSHRPDE4A | |
| SCHEMBL4429271 | 0.80 | LHCGR (0.54) | LHCGRFSHRBRAFTSHRPDE4A | |
| SCHEMBL5030680 | 0.79 | LHCGR (0.53) | LHCGRFSHRBRAFTSHRPDE4A | |
| SCHEMBL5026102 | 0.79 | LHCGR (0.53) | LHCGRFSHRBRAFTSHRPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7618963-B2 | Bicyclic heteroaromatic compounds | N.V. ORGANON (NL) | 2009-11-17 | — | — | US | disclosed |
| US-20070197527-A1 | Bicyclic heteroaromatic compounds | N.V. ORGANON (NL) | 2007-08-23 | — | — | US | disclosed |
| CN-1247594-C | Bicyclic heteroaromatic compounds | OKZO NOBEL N V (NL) | 2006-03-29 | — | — | CN | disclosed |
| CN-1462273-A | Bicyclic heteroaromatic compounds | OKZO NOBEL N V (NL) | 2003-12-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197527-A1 | Bicyclic heteroaromatic compounds | NR5A1, CYP19A1, FSHR | LHCGR 10/4885FSHR 3/4885BRAF 4242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.