SCHEMBL5037173

SCHEMBL5037173

CSc1nc(-c2cccc(NS(=O)(=O)CCN3CCN(C)CC3)c2)c2c(N)c(C(=O)NC(C)(C)C)sc2n1

nearest known ligand 0.62

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LHCGR P22888 17/20 0.62
FSHR P23945 5/20 0.61
TSHR P16473 2/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5034058 0.94 LHCGR (0.63) LHCGRFSHRTSHR
SCHEMBL5036592 0.94 LHCGR (0.61) LHCGRFSHRTSHR
SCHEMBL4423893 0.91 LHCGR (0.48) LHCGRFSHRTSHR
SCHEMBL4421281 0.85 LHCGR (0.50) LHCGRFSHRTSHR
SCHEMBL4432274 0.84 LHCGR (0.48) LHCGRFSHRTSHR
SCHEMBL5043509 0.84 LHCGR (0.65) LHCGRFSHRTSHR
SCHEMBL4429147 0.81 LHCGR (0.70) LHCGRFSHRTSHR
SCHEMBL30673520 0.80 LHCGR (0.67) LHCGRFSHRTSHR
SCHEMBL5028832 0.80 LHCGR (0.67) LHCGRFSHRTSHR
SCHEMBL5028842 0.80 LHCGR (0.67) LHCGRFSHRTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1886999-A2 Bicyclic heteroaromatic compound N.V. Organon (NL) 2008-02-13 EP disclosed