SCHEMBL4424405

SCHEMBL4424405

C=CC(=O)NC1CC(C)(C)NC(C)(C)C1

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.51
RECQL P46063 1/20 0.49
POLB P06746 2/20 0.47
ALDH1A1 P00352 1/20 0.44
EZH2 Q15910 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.43
ATM Q13315 1/20 0.43
HSD17B10 Q99714 1/20 0.43
HTT P42858 1/20 0.43
GLA P06280 1/20 0.43
KMT2A Q03164 3/20 0.42
MEN1 O00255 2/20 0.42
KDM4E B2RXH2 1/20 0.42
PKM P14618 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11653677 0.87 GAA (0.48) GAARECQLPOLBALDH1A1EZH2
SCHEMBL18073078 0.82 APLNR (0.37) GAAPOLBALDH1A1HTT
SCHEMBL108540 0.80 RECQL (0.47) GAARECQLPOLBALDH1A1EZH2
SCHEMBL108538 0.80 RECQL (0.47) GAARECQLPOLBALDH1A1EZH2
SCHEMBL26680180 0.79 POLB (0.56) GAARECQLPOLBALDH1A1EZH2
SCHEMBL8372879 0.79 GAA (0.36) GAARECQLPOLBALDH1A1EZH2
SCHEMBL3050149 0.79 POLB (0.56) GAARECQLPOLBALDH1A1EZH2
SCHEMBL11128573 0.79 RECQL (0.53) GAARECQLPOLBALDH1A1EZH2
SCHEMBL3295977 0.78 RECQL (0.57) GAARECQLPOLBALDH1A1EZH2
SCHEMBL10525290 0.78 RECQL (0.57) GAARECQLPOLBALDH1A1EZH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10287381-B2 Non-halogenated flame retardant hindered amine light stabilizer impact modifiers INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2019-05-14 US claimed
US-20190048114-A1 NON-HALOGENATED FLAME RETARDANT HINDERED AMINE LIGHT STABILIZER IMPACT MODIFIERS INTERNATIONAL BUSINESS MACHINES CORPORATION 2019-02-14 US claimed
CN-108864635-A A kind of preparation method on PVC roll material floor 合肥华盖光伏科技有限公司 2018-11-23 CN claimed
US-10125206-B1 Non-halogenated flame retardant hindered amine light stabilizer impact modifiers INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-11-13 US claimed
US-10030090-B1 Non-halogenated flame retardant hindered amine light stabilizer impact modifiers INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-07-24 US claimed
CN-102942753-B Preparation method of modified polyvinyl chloride CHANGCHUN APPLIED CHEMISTRY 2014-12-10 CN claimed
JP-4298915-B2 2009-07-22 JP claimed
CN-100432160-C Water-based reaction type hindered amine use, formula and method for in-situ photostabilization of coating layer UNIV SHANTOU (CN) 2008-11-12 CN claimed
CN-1640957-A Water-based reaction type hindered amine use, formula and method for in-situ photostabilization of coating layer UNIV SHANTOU (CN) 2005-07-20 CN claimed
EP-1058698-B1 PREPARATION FOR PREVENTION AND HEALING OF INFLAMMATION AFFECTIONS USTAV MAKROMOLEKULARNI CHEMIE (CZ) 2004-07-28 EP claimed
US-6610284-B1 Derivatives of sterically hindered amines selected from the group consisting of: soluble polymers or copolymers prepared by radical polymerization in the presence of 0.01 to 10% by weight, of initiators prepared:in a polymerization mixture INSTITUTE OF MACROMOLECULAR CHEMISTRY (CZ) 2003-08-26 US claimed
JP-2001525340-A 2001-12-11 JP claimed
EP-1058698-A1 PREPARATION FOR PREVENTION AND HEALING OF INFLAMMATION AFFECTIONS USTAV MAKROMOLEKULARNI CHEMIE AKADEMIE VED CESKE REPUBLIKY (CZ) 2000-12-13 EP claimed
WO-1999064563-A1 POLYMER CARRIER FOR CULTIVATION OF KERATINOCYTES ÚSTAV MAKROMOLEKULÁRNÍ CHEMIE AKADEMIE VĚD ČESKÉ REPUBLIKY (CZ) 1999-12-16 WO claimed
WO-1999028359-A1 PREPARATION FOR PREVENTION AND HEALING OF INFLAMMATION AFFECTIONS ÚSTAV MAKROMOLEKULÁRNÍ CHEMIE AKADEMIE VED C^¿ESKÉ REPUBLIKY (CZ) 1999-06-10 WO claimed
EP-4714527-A1 GAS RECOVERY DEVICE AND GAS RECOVERY METHOD JCCL, Inc. (JP) 2026-03-25 EP disclosed
EP-4714526-A1 GAS RECOVERY DEVICE AND GAS RECOVERY METHOD JCCL, Inc. (JP) 2026-03-25 EP disclosed
US-4369274-A Hindered amine light stabilizers for polymers AMERICAN CYANAMID COMPANY (US) 1983-01-18 US disclosed
US-4362831-A A HINDERED AND HETEROCYCLIC AMINE WITH A THIOALKANOIC ACID AMIDE ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1982-12-07 US disclosed
EP-0001803-A1 Polymers of substituted piperidine, their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1979-05-16 EP disclosed