SCHEMBL108538

SCHEMBL108538

C/C=C/C(=O)NC1CC(C)(C)NC(C)(C)C1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.47
POLB P06746 2/20 0.46
GAA P10253 2/20 0.45
ALDH1A1 P00352 1/20 0.43
EZH2 Q15910 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.42
ATM Q13315 1/20 0.42
HSD17B10 Q99714 1/20 0.42
HTT P42858 1/20 0.42
GLA P06280 1/20 0.42
KMT2A Q03164 3/20 0.41
MEN1 O00255 2/20 0.41
KDM4E B2RXH2 1/20 0.41
PKM P14618 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL108540 1.00 RECQL (0.47) RECQLPOLBGAAALDH1A1EZH2
SCHEMBL26680180 0.84 POLB (0.56) RECQLPOLBGAAALDH1A1EZH2
SCHEMBL3050149 0.84 POLB (0.56) RECQLPOLBGAAALDH1A1EZH2
SCHEMBL26680173 0.81 GAA (0.46) RECQLPOLBGAAALDH1A1EZH2
SCHEMBL28117145 0.81 GAA (0.46) RECQLPOLBGAAALDH1A1EZH2
SCHEMBL4424405 0.80 GAA (0.51) RECQLPOLBGAAALDH1A1EZH2
SCHEMBL6754431 0.77 PTPRC (0.43) POLBGAAHTTKMT2AKDM4E
SCHEMBL5416795 0.77 POLB (0.35) POLBGAAHTTKMT2AKDM4E
SCHEMBL5416803 0.77 POLB (0.35) POLBGAAHTTKMT2AKDM4E
SCHEMBL11128573 0.77 RECQL (0.53) RECQLPOLBGAAALDH1A1EZH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 432 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7271213-B2 Pigment dispersing resin KANSAI PAINT CO., LTD. (JP) 2007-09-18 US claimed
US-6994745-B2 Pigment dispersing resin KANSAI PAINT CO., LTD. (JP) 2006-02-07 US claimed
US-20050252418-A1 Copolymer of an unsaturated monomer containing an ionic functional groups such as, tert-amino, quaternary ammonium salt and sulfonic acid; an polyethoxylated acrylate, ultraviolet absorbing unsaturated monomer and other HOSHIDA YUKO 2005-11-17 US claimed
EP-1118632-B1 Composite particles, composite particle dispersion composition, and method of preparing composite particle dispersion composition JSR CORP (JP) 2005-04-13 EP claimed
US-6541114-B2 Composite particles, composite particle dispersion composition, and method of preparing composite particle dispersion composition JSR CORPORATION (JP) 2003-04-01 US claimed
US-20030045637-A1 Pigment dispersing resin KANSAI PAINT CO., LTD. (JP) 2003-03-06 US claimed
EP-1247821-A2 Pigment dispersing resin KANSAI PAINT CO., LTD. (JP) 2002-10-09 EP claimed
US-20010033932-A1 Composite particles, composite particle dispersion composition, and method of preparing composite particle dispersion composition JSR CORPORATION (JP) 2001-10-25 US claimed
EP-1118632-A2 Composite particles, composite particle dispersion composition, and method of preparing composite particle dispersion composition JSR Corporation (JP) 2001-07-25 EP claimed
US-12637574-B2 Coating composition KANSAI PAINT CO., LTD. (JP) 2026-05-26 US disclosed
US-12630654-B2 Emulsion particle-containing aqueous dispersion NIPPON SHOKUBAI CO., LTD. (JP) 2026-05-19 US disclosed
US-12629926-B2 Decorative sheet and decorative material DAI NIPPON PRINTING CO., LTD. (JP) 2026-05-19 US disclosed
US-12590214-B2 Ink-jet ink NIPPON SHOKUBAI CO., LTD. (JP) 2026-03-31 US disclosed
US-12576431-B2 Method for forming multi-layer coating film KANSAI PAINT CO., LTD. (JP) 2026-03-17 US disclosed
EP-0567654-A1 HIGHLY WEATHER-RESISTANT ONE-PACK CROSS-LINKING EMULSION NIPPON SHOKUBAI CO., LTD. (JP) 1993-11-03 EP disclosed
US-5239028-A ULTRAVIOLET-STABLE COPOLYMER, PROCESS FOR PRODUCING THE SAME, AND COATING COMPOSITION CONTAINING THE SAME NIPPON SHOKUBAI, CO. (JP) 1993-08-24 US disclosed
EP-0293871-B1 LIGHT STABILIZED, STARSHAPED MICROPARTICLES CIBA-GEIGY AG (CH) 1993-03-17 EP disclosed
US-4880859-A GROUP TRANSFER POLYMERIZATION, COATINGS CIBA-GEIGY CORPORATION (US) 1989-11-14 US disclosed
EP-0337744-A2 Ultraviolet-stable copolymer. Process for producing the same, and coating composition containing the same NIPPON SHOKUBAI CO., LTD. (JP) 1989-10-18 EP disclosed
EP-0293871-A2 Light stabilized, starshaped microparticles CIBA-GEIGY AG (CH) 1988-12-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12629926-B2 Decorative sheet and decorative material TLL1, POT1, TLL2 RECQL 882/4885POLB 1499/4885GAA 3322/4885
US-12637574-B2 Coating composition ITGB3, ATG13, C9 RECQL 1668/4885POLB 2215/4885GAA 1753/4885
US-12630654-B2 Emulsion particle-containing aqueous dispersion CLTB, CLTA, APOB RECQL 2059/4885POLB 38/4885GAA 3443/4885
US-12576431-B2 Method for forming multi-layer coating film SPIN3, SLC6A3, MARK3 RECQL 3346/4885POLB 2150/4885GAA 3991/4885
US-12590214-B2 Ink-jet ink MIF, ELANE, SEM1 RECQL 1823/4885POLB 1757/4885GAA 4658/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.