Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 13/20 | 0.38 |
| ▸ | ITGAV | P06756 | 7/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | F2R | P25116 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6604248 | 1.00 | GAA (0.38) | GAAITGB3ITGAVITGA2BMEN1 | |
| SCHEMBL4430638 | 0.93 | GAA (0.38) | GAAITGB3ITGAVITGA2BF2R | |
| SCHEMBL7697653 | 0.91 | ITGB3 (0.41) | GAAITGB3ITGAVITGA2BF2R | |
| SCHEMBL4436751 | 0.91 | ITGB3 (0.41) | GAAITGB3ITGAVITGA2BF2R | |
| SCHEMBL4431178 | 0.91 | ITGB3 (0.41) | GAAITGB3ITGAVITGA2BF2R | |
| SCHEMBL4424713 | 0.90 | MEN1 (0.38) | GAAITGB3ITGAVITGA2BMEN1 | |
| SCHEMBL4423197 | 0.90 | ITGB3 (0.40) | GAAITGB3ITGAVITGA2BMEN1 | |
| SCHEMBL4436812 | 0.90 | KMT2A (0.39) | GAAITGB3ITGAVITGA2BKMT2A | |
| SCHEMBL6763118 | 0.89 | CTSA (0.40) | — | |
| SCHEMBL4426944 | 0.89 | FPR1 (0.39) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189881-B2 | PROPANOIC ACID DERIVATIVES THAT INHIBIT THE BINDING OF INTEGRINS TO THEIR RECEPTORS | ENCYSIVE PHARMACEUTICALS INC (US) | 2013-01-23 | — | — | EP | disclosed |
| EP-1213288-B1 | Propanoic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC (US) | 2009-01-14 | — | — | EP | disclosed |
| EP-1189881-B1 | PROPANOIC ACID DERIVATIVES THAT INHIBIT THE BINDING OF INTEGRINS TO THEIR RECEPTORS | TEXAS BIOTECHNOLOGY CORP (US) | 2004-09-29 | — | — | EP | disclosed |
| EP-1213288-A1 | Propanoic acid derivatives that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2002-06-12 | — | — | EP | disclosed |