SCHEMBL4424767

SCHEMBL4424767

CCOP(=O)(OCC)Oc1ccc(Cl)cc1

nearest known ligand 0.60

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.60
CA1 P00915 1/20 0.60
BCHE P06276 1/20 0.60
ACHE P22303 1/20 0.60
MEN1 O00255 4/20 0.52
KMT2A Q03164 4/20 0.52
POLB P06746 1/20 0.49
GAA P10253 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.46
TSHR P16473 2/20 0.45
CYP3A4 P08684 1/20 0.45
NR1I2 O75469 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
HPGD P15428 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11579723 0.90 CA2 (0.51) CA2CA1BCHEACHEMEN1
SCHEMBL5026807 0.90 CA2 (0.70) CA2CA1BCHEACHEMEN1
SCHEMBL10786081 0.90 CA1 (0.50) CA2CA1BCHEACHEMEN1
SCHEMBL3234851 0.84 CYP3A4 (0.53) CA2CA1BCHEACHEMEN1
SCHEMBL3294100 0.82 TSHR (0.69) CA2CA1BCHEACHEMEN1
SCHEMBL20710745 0.82 CA1 (0.62) CA2CA1BCHEACHEMEN1
SCHEMBL28395895 0.81 CA2 (0.57) CA2CA1BCHEACHEMEN1
SCHEMBL28444068 0.81 MEN1 (0.48) CA2CA1BCHEACHEMEN1
SCHEMBL4431205 0.81 CYP3A4 (0.50) MEN1KMT2AGAACYP3A4L3MBTL1
SCHEMBL1059937 0.81 MEN1 (0.67) CA2CA1MEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106128947-B A kind of lithographic method of multi-layer graphene 山东赛帝格新材料有限责任公司 2019-01-29 CN claimed
CN-106128947-A A kind of lithographic method of multi-layer graphene 烟台市烯能新材料股份有限公司 2016-11-16 CN claimed
CN-115650883-A Method for synthesizing aniline and its derivative by using nickel-ammonium complex as ammonia slow-release agent 陕西师范大学 2023-01-31 CN disclosed
CN-106128947-B A kind of lithographic method of multi-layer graphene 山东赛帝格新材料有限责任公司 2019-01-29 CN disclosed
CN-106128947-A A kind of lithographic method of multi-layer graphene 烟台市烯能新材料股份有限公司 2016-11-16 CN disclosed
EP-2097428-A2 BUTYRYLCHOLINESTERASE INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES Mgp Biotechnologies, Inc. (US) 2009-09-09 EP disclosed
WO-2008055249-A2 BUTYRYLCHOLINESTERASE INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES MGP BIOTECHNOLOGIES, INC. (US) 2008-05-08 WO disclosed
EP-1572704-A1 PHOSPHORUS-CONTAINING PIPERAZINE DERIVATIVES AS CCR1 ANTAGONISTS Pfizer Products Inc. (US) 2005-09-14 EP disclosed
US-20040127465-A1 Novel phosphorus-containing derivatives PFIZER INC 2004-07-01 US disclosed
WO-2004055031-A1 PHOSPHORUS-CONTAINING PIPERAZINE DERIVATIVES AS CCR1 ANTAGONISTS PFIZER PRODUCTS INC. (US) 2004-07-01 WO disclosed
US-4003966-A Selective phosphorylation process MOBIL OIL CORPORATION (US) 1977-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040127465-A1 Novel phosphorus-containing derivatives SLC34A2, SLC34A1, SLC20A1 CA2 81/4885CA1 644/4885BCHE 2592/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.