Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CA9 | Q16790 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CCR9 | P51686 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | S100A4 | P26447 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11402428 | 0.86 | KDM4E (0.61) | KDM4ECA2CA9CA12CA1 | |
| SCHEMBL4432198 | 0.81 | HSPA1A (0.61) | KDM4ECCR9KMT2ANPC1MAPT | |
| SCHEMBL5151001 | 0.80 | KDM4E (0.71) | KDM4ECA2CA9CA12CA1 | |
| SCHEMBL31259847 | 0.80 | KDM4E (0.71) | KDM4ECA2CA9CA12CA1 | |
| SCHEMBL3376342 | 0.80 | CCR9 (0.47) | KDM4ECYP1A2CYP2C9CYP2C19CCR9 | |
| SCHEMBL4419914 | 0.80 | CCR9 (0.47) | KDM4ECYP1A2CYP2C9CYP2C19CCR9 | |
| SCHEMBL11309121 | 0.79 | KDM4E (0.62) | KDM4ECA2CA9CA12CA1 | |
| SCHEMBL11308425 | 0.79 | KDM4E (0.62) | KDM4ECA2CA9CA12CA1 | |
| SCHEMBL4409822 | 0.79 | KDM4E (0.58) | KDM4ECA2CA9CA12CA1 | |
| SCHEMBL29168850 | 0.78 | KMT2A (0.57) | KDM4ECA2CA9CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362369-B1 | — | — | None | — | — | US | disclosed |
| EP-1700844-B1 | Phthalic acid diamide derivatives, agricultural and horticultural insecticides and a method for application of the insecticides | NIHON NOHYAKU CO LTD (JP) | 2009-01-14 | — | — | EP | disclosed |
| EP-1700844-A1 | Phthalic acid diamide derivatives, agricultural and horticultural insecticides and a method for application of the insecticides | Nihon Nohyaku Co., Ltd. (JP) | 2006-09-13 | — | — | EP | disclosed |
| EP-0919542-B1 | Phthalic acid diamide derivatives, agricultural and horticultural insecticides, and a method for application of the insecticides | NIHON NOHYAKU CO LTD (JP) | 2006-08-23 | — | — | EP | disclosed |
| EP-1447396-A1 | Phthalic acid diamide derivatives, agriculture and horticultural insecticides, and a method for application of the insecticides | NIHON NOHYAKU CO., LTD. (JP) | 2004-08-18 | — | — | EP | disclosed |
| US-6559341-B2 | Phthalic acid diamide derivatives, fluorine-containing aniline compounds as starting material, agricultural and horticultural insecticides, and a method for application of the insecticides | NIHON NOHYAKU CO., LTD. (JP) | 2003-05-06 | — | — | US | disclosed |
| US-20030055287-A1 | Phthalic acid diamide derivatives, fluorine-containing aniline compounds as starting material, agricultural and horticultural insecticides, and a method for application of the insecticides | AIR MOTION TECHNOLOGIES, LLC | 2003-03-20 | — | — | US | disclosed |
| US-6362369-B2 | CONTROLLING INSECTS IN CROPS | NIHON NOHYAKU CO., LTD. (JP) | 2002-03-26 | — | — | US | disclosed |
| US-20010041814-A1 | PHTHALIC ACID DIAMIDE DERIVATIVES FLUORINE-CONTAINING ANILINE COMPOUNDS AS STARTING MATERIAL, AGRICULTURAL AND HORTICULTURAL INSECTICIDES, AND A METHOD FOR APPLICATION OF THE INSECTICIDES | NIHON NOHYAKU CO., LTD. (JP) | 2001-11-15 | — | — | US | disclosed |
| EP-0919542-A2 | Phthalic acid diamide derivatives, agricultural and horticultural insecticides, and a method for application of the insecticides | NIHON NOHYAKU CO., LTD. (JP) | 1999-06-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010041814-A1 | PHTHALIC ACID DIAMIDE DERIVATIVES FLUORINE-CONTAINING ANILINE COMPOUNDS AS STARTING MATERIAL, AGRICULTURAL AND HORTICULTURAL INSECTICIDES, AND A METHOD FOR APPLICATION OF THE INSECTICIDES | DDT, AFF1, BCL2L2 | KDM4E 2453/4885CA2 460/4885CA9 1140/4885 |
| US-20030055287-A1 | Phthalic acid diamide derivatives, fluorine-containing aniline compounds as starting material, agricultural and horticultural insecticides, and a method for application of the insecticides | DDT, BCL2A1, BCL2L2 | KDM4E 2584/4885CA2 339/4885CA9 940/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.