SCHEMBL5151001

SCHEMBL5151001

O=C1c2cccc([N+](=O)[O-])c2C(=O)N1c1ccccc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.71
CA2 P00918 3/20 0.66
CA9 Q16790 3/20 0.66
CA12 O43570 2/20 0.66
CA1 P00915 2/20 0.66
LMNA P02545 1/20 0.66
HSPA1A P0DMV8 1/20 0.59
PABPC1 P11940 1/20 0.59
CYP1A2 P05177 1/20 0.58
CYP3A4 P08684 1/20 0.58
CYP2C9 P11712 1/20 0.58
CYP2C19 P33261 1/20 0.58
SCN2A Q99250 2/20 0.55
S100A4 P26447 2/20 0.53
PTPRC P08575 1/20 0.53
KMT2A Q03164 2/20 0.49
ATM Q13315 1/20 0.49
MEN1 O00255 1/20 0.49
DDB1 Q16531 1/20 0.48
CRBN Q96SW2 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31259847 1.00 KDM4E (0.71) KDM4ECA2CA9CA12CA1
SCHEMBL11308425 0.87 KDM4E (0.62) KDM4ECA2CA9CA12CA1
SCHEMBL11309121 0.87 KDM4E (0.62) KDM4ECA2CA9CA12CA1
SCHEMBL4230682 0.86 CA9 (0.60) KDM4ECA2CA9CA12CA1
SCHEMBL9806781 0.86 LMNA (0.81) KDM4ECA2CA9CA12CA1
SCHEMBL11402428 0.85 KDM4E (0.61) KDM4ECA2CA9CA12CA1
SCHEMBL9502422 0.85 KDM4E (0.61) KDM4ECA2CA9CA12CA1
Hydrochloric Acid SCHEMBL11406824 0.85 KDM4E (0.61) KDM4ECA2CA9CA12CA1
SCHEMBL11312354 0.84 CA2 (0.66) KDM4ECA2CA9CA12CA1
SCHEMBL4231252 0.84 TYMS (0.65) KDM4ECA2CA9CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119504556-A Bisphenol phthaloyl Process for producing imine 潍坊弘润石化科技有限公司 2025-02-25 CN claimed
CN-108117505-A A kind of preparation method for synthesizing diphenyl ether imidodicarbonic diamide 杜庶铭 2018-06-05 CN claimed
CN-103497337-B A kind of preparation method of Polythioetherimide NINGBO INSTITUTE OF MATERIALS TECHNOLOGY & ENGINEERING, CHINESE ACADEMY OF SCIENCES (CN) 2015-11-18 CN claimed
US-20070043011-A1 Substituted benzanilide compound and noxious organism controlling agent MITSUBISHI TANABE PHARMA CORPORATION (JP) 2007-02-22 US claimed
EP-1671941-A1 SUBSTITUTED BENZANILIDE COMPOUND AND PEST CONTROL AGENT Nissan Chemical Industries, Ltd. (JP) 2006-06-21 EP claimed
US-20050250822-A1 Substituted benzanilide compound and noxious organism controlling agent NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2005-11-10 US claimed
EP-1538138-A1 SUBSTITUTED BENZANILIDE COMPOUND AND PEST CONTROL AGENT NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 2005-06-08 EP claimed
US-5208346-A Simplified process for the preparation of aromatic bismides GENERAL ELECTRIC COMPANY (US) 1993-05-04 US claimed
US-4054584-A ALKALI METAL SULFIDES GENERAL ELECTRIC COMPANY (US) 1977-10-18 US claimed
US-3957862-A FROM A NITRO-PHTHALIMIDE AND ALKALI DIPHENOXIDE GENERAL ELECTRIC COMPANY (US) 1976-05-18 US claimed
CN-119504556-A Bisphenol phthaloyl Process for producing imine 潍坊弘润石化科技有限公司 2025-02-25 CN disclosed
CN-110483454-B Preparation method of aromatic diether dianhydride 湖南师范大学 2023-04-25 CN disclosed
CN-110483454-A A kind of preparation method of two ether dianhydride of aromatic series UNIV HUNAN NORMAL 2019-11-22 CN disclosed
CN-108117505-A A kind of preparation method for synthesizing diphenyl ether imidodicarbonic diamide 杜庶铭 2018-06-05 CN disclosed
CN-103497337-B A kind of preparation method of Polythioetherimide NINGBO INSTITUTE OF MATERIALS TECHNOLOGY & ENGINEERING, CHINESE ACADEMY OF SCIENCES (CN) 2015-11-18 CN disclosed
US-4011198-A METHOD FOR MAKING POLYETHERIMIDES GENERAL ELECTRIC COMPANY (US) 1977-03-08 US disclosed
US-3989712-A Thio-bis(phthalimides) GENERAL ELECTRIC COMPANY (US) 1976-11-02 US disclosed
US-3957862-A FROM A NITRO-PHTHALIMIDE AND ALKALI DIPHENOXIDE GENERAL ELECTRIC COMPANY (US) 1976-05-18 US disclosed
US-3956320-A FIREPROOFING GENERAL ELECTRIC COMPANY (US) 1976-05-11 US disclosed
US-3933862-A Aromatic dithio dianhydrides GENERAL ELECTRIC COMPANY (US) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070043011-A1 Substituted benzanilide compound and noxious organism controlling agent L3MBTL1, L3MBTL3, L3MBTL4 KDM4E 2403/4885CA2 144/4885CA9 1605/4885
US-20050250822-A1 Substituted benzanilide compound and noxious organism controlling agent GCN1, L3MBTL3, L3MBTL4 KDM4E 3386/4885CA2 249/4885CA9 1638/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.