Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | ERN1 | O75460 | 1/20 | 0.53 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | RXRA | P19793 | 1/20 | 0.51 |
| ▸ | RXRB | P28702 | 1/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | DDT | P30046 | 1/20 | 0.50 |
| ▸ | CD74 | P04233 | 1/20 | 0.50 |
| ▸ | MIF | P14174 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27574419 | 0.98 | KMO (0.61) | KMOALDH1A1HPGDBCL2L1HSD17B10 | |
| SCHEMBL29574762 | 0.89 | KMO (0.51) | KMOALDH1A1HPGDBCL2L1HSD17B10 | |
| SCHEMBL30259065 | 0.88 | KMO (0.73) | KMOPTGER1CA12CA1CA2 | |
| SCHEMBL2213546 | 0.88 | KMO (0.73) | KMOPTGER1CA12CA1CA2 | |
| SCHEMBL407375 | 0.87 | KMO (0.56) | KMOALDH1A1HPGDHSD17B10ERN1 | |
| SCHEMBL382724 | 0.86 | KMO (0.70) | KMOPTGER1CA12CA1CA2 | |
| SCHEMBL1707626 | 0.86 | KMO (0.70) | KMOPTGER1CA12CA1CA2 | |
| 2-Phenylphenol SCHEMBL150515 | 0.86 | ALDH1A1 (0.71) | KMOALDH1A1HPGDBCL2L1HSD17B10 | |
| Biphenyl SCHEMBL5316961 | 0.86 | KMO (0.61) | KMOERN1PTGER1CA12CA1 | |
| SCHEMBL4368940 | 0.86 | FOLH1 (0.60) | KMOERN1PTGER1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4728340-B2 | — | — | 2011-07-20 | — | — | JP | claimed |
| JP-2008517932-A | — | — | 2008-05-29 | — | — | JP | claimed |
| EP-1805155-A1 | THROMBOPOIETIN ACTIVITY MODULATING COMPOUNDS AND METHODS | LIGAND PHARMACEUTICALS, INC. (US) | 2007-07-11 | — | — | EP | claimed |
| WO-2006047344-A1 | THROMBOPOIETIN ACTIVITY MODULATING COMPOUNDS AND METHODS | LIGAND PHARMACEUTICALS, INC. (US) | 2006-05-04 | — | — | WO | claimed |
| EP-1294378-A4 | THROMBOPOIETIN MIMETICS | SMITHKLINE BEECHAM CORP (US) | 2004-01-28 | — | — | EP | claimed |
| EP-1294378-A2 | THROMBOPOIETIN MIMETICS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-03-26 | — | — | EP | claimed |
| WO-2001089457-A2 | THROMBOPOIETIN MIMETICS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-11-29 | — | — | WO | claimed |
| CN-116178687-B | Wholly aromatic liquid crystal polyester and preparation method and application thereof | 金发科技股份有限公司 | 2025-06-24 | — | — | CN | disclosed |
| CN-119816306-A | Treatment of Aplastic Anemia (AA) | 载度思生命科学有限公司 | 2025-04-11 | — | — | CN | disclosed |
| EP-3474834-B1 | STIMULATING PLATELET FORMATION WITH BEZAFIBRATE, RESVERATROL OR SRT1720 TO TREAT THROMBOCYTOPENIA | THE GENERAL HOSPITAL CORP DBA MASSACHUSETTS GENERAL HOSPITAL (US) | 2025-04-09 | — | — | EP | disclosed |
| CN-116874428-B | PNPO inhibitor with multiple myeloma resisting effect, and preparation method and application thereof | 南京中医药大学 | 2025-01-28 | — | — | CN | disclosed |
| CN-116874428-A | PNPO inhibitor with multiple myeloma resisting effect, and preparation method and application thereof | 南京中医药大学 | 2023-10-13 | — | — | CN | disclosed |
| CN-116178687-A | Wholly aromatic liquid crystal polyester and preparation method and application thereof | 金发科技股份有限公司 | 2023-05-30 | — | — | CN | disclosed |
| WO-2006047344-A1 | THROMBOPOIETIN ACTIVITY MODULATING COMPOUNDS AND METHODS | LIGAND PHARMACEUTICALS, INC. (US) | 2006-05-04 | — | — | WO | disclosed |
| EP-1294378-A4 | THROMBOPOIETIN MIMETICS | SMITHKLINE BEECHAM CORP (US) | 2004-01-28 | — | — | EP | disclosed |
| CN-1444477-A | Thrombopoietin mimetics | SMITHKLINE BEECHAM CORP (US) | 2003-09-24 | — | — | CN | disclosed |
| EP-1294378-A2 | THROMBOPOIETIN MIMETICS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-03-26 | — | — | EP | disclosed |
| WO-2001089457-A2 | THROMBOPOIETIN MIMETICS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-11-29 | — | — | WO | disclosed |
| US-4044049-A | Phenyl benzoic acid compounds | MERCK & CO., INC. (US) | 1977-08-23 | — | — | US | disclosed |
| US-3741985-A | PHENYL-BENZODIOXANE DERIVATIVES | SYNTEX CORP | 1973-06-26 | — | — | US | disclosed |