Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.39 |
| ▸ | HMGCR | P04035 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2932467 | 1.00 | TSHR (0.45) | TSHRALDH1A1TET2HMGCRCHRM1 | |
| SCHEMBL581582 | 0.77 | — | — | |
| SCHEMBL79613 | 0.77 | — | — | |
| SCHEMBL2327762 | 0.77 | — | — | |
| SCHEMBL4963143 | 0.77 | TSHR (0.50) | TSHRALDH1A1TET2HMGCRCHRM1 | |
| SCHEMBL126425 | 0.76 | HMGCR (0.55) | TSHRALDH1A1TET2HMGCRCHRM1 | |
| SCHEMBL13686398 | 0.76 | ALDH1A1 (0.43) | TSHRALDH1A1TET2HMGCRCHRM1 | |
| SCHEMBL4381836 | 0.74 | TSHR (0.40) | TSHRALDH1A1TET2HMGCRCHRM1 | |
| SCHEMBL6755733 | 0.74 | — | — | |
| SCHEMBL9247690 | 0.74 | TSHR (0.40) | TSHRALDH1A1TET2HMGCRCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11787900-B2 | Biodegradable sustainable polyesters | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-10-17 | — | — | US | claimed |
| US-20230151142-A1 | BIODEGRADABLE SUSTAINABLE POLYESTERS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2023-05-18 | — | — | US | claimed |
| WO-2023081515-A1 | BIODEGRADABLE SUSTAINABLE POLYESTERS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-05-11 | — | — | WO | claimed |
| US-11787900-B2 | Biodegradable sustainable polyesters | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-10-17 | — | — | US | disclosed |
| US-20230151142-A1 | BIODEGRADABLE SUSTAINABLE POLYESTERS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2023-05-18 | — | — | US | disclosed |
| WO-2023081515-A1 | BIODEGRADABLE SUSTAINABLE POLYESTERS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-05-11 | — | — | WO | disclosed |
| WO-2018157942-A1 | CELL-FREE SYNTHESIS OF ISOTOPIC LABELLED PROTEINS FROM AMINO-ACIDS PRECURSORS | NMR - BIO (FR) | 2018-09-07 | — | — | WO | disclosed |
| US-8311790-B2 | Reverse engineering genome-scale metabolic network reconstructions for organisms with incomplete genome annotation and developing constraints using proton flux states and numerically-determined sub-systems | UNIVERSITY OF DELAWARE (US) | 2012-11-13 | — | — | US | disclosed |
| US-20090259451-A1 | REVERSE ENGINEERING GENOME-SCALE METABOLIC NETWORK RECONSTRUCTIONS FOR ORGANISMS WITH INCOMPLETE GENOME ANNOTATION AND DEVELOPING CONSTRAINTS USING PROTON FLUX STATES AND NUMERICALLY-DETERMINED SUB-SYSTEMS | UNIVERSITY OF DELAWARE (US) | 2009-10-15 | — | — | US | disclosed |