Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.38 |
| ▸ | HMGCR | P04035 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9882905 | 0.78 | — | — | |
| SCHEMBL4425053 | 0.76 | TSHR (0.45) | ALDH1A1TSHRTET2HMGCRCHRM1 | |
| SCHEMBL2932467 | 0.76 | TSHR (0.45) | ALDH1A1TSHRTET2HMGCRCHRM1 | |
| SCHEMBL126425 | 0.74 | HMGCR (0.55) | ALDH1A1TSHRTET2HMGCRCHRM1 | |
| SCHEMBL13686379 | 0.72 | — | — | |
| SCHEMBL29365048 | 0.72 | ALDH1A1 (0.41) | ALDH1A1TSHRTET2HMGCRCHRM1 | |
| SCHEMBL860611 | 0.67 | — | — | |
| SCHEMBL28634491 | 0.67 | LMNA (0.42) | ALDH1A1TSHR | |
| SCHEMBL16045720 | 0.65 | ALDH1A1 (0.44) | ALDH1A1TSHRHMGCRCHRM1TBXA2R | |
| SCHEMBL15105881 | 0.65 | TSHR (0.38) | ALDH1A1TSHRTET2HMGCRCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7595402-B2 | Prodrugs of selective androgen receptor modulators and methods of use thereof | GTX, INC. (US) | 2009-09-29 | — | — | US | disclosed |