Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31126376 | 1.00 | TLR7 (0.59) | TLR7NUDT1 | |
| SCHEMBL20284131 | 0.92 | TLR7 (0.57) | TLR7NUDT1 | |
| SCHEMBL20380003 | 0.92 | TLR7 (0.57) | TLR7NUDT1 | |
| SCHEMBL31126373 | 0.92 | TLR7 (0.57) | TLR7NUDT1 | |
| SCHEMBL20284132 | 0.90 | TLR7 (0.57) | TLR7NUDT1 | |
| SCHEMBL24366070 | 0.90 | TLR7 (0.67) | TLR7 | |
| SCHEMBL17676771 | 0.90 | TLR7 (0.59) | TLR7NUDT1 | |
| SCHEMBL20647710 | 0.89 | TLR7 (0.54) | TLR7NUDT1 | |
| SCHEMBL24863315 | 0.89 | TLR7 (0.54) | TLR7NUDT1 | |
| SCHEMBL822735 | 0.89 | TLR7 (0.58) | TLR7NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3568162-B1 | MULTI-ARM POLYMER CONJUGATES OF TLR AGONIST COMPOUNDS AND RELATED IMMUNOTHERAPEUTIC TREATMENT METHODS | NEKTAR THERAPEUTICS (US) | 2026-03-18 | — | — | EP | disclosed |
| US-12214045-B2 | Multi-arm polymer conjugates of TLR agonist compounds and related immunotherapeutic treatment methods | NEKTAR THERAPEUTICS (US) | 2025-02-04 | — | — | US | disclosed |
| US-12054553-B2 | Immunotherapeutic tumor treatment method | NEKTAR THERAPEUTICS (US) | 2024-08-06 | — | — | US | disclosed |
| US-12030940-B2 | Immunotherapeutic tumor treatment method | NEKTAR THERAPEUTICS (US) | 2024-07-09 | — | — | US | disclosed |
| US-20230372511-A1 | ANTIBODY-IMMUNE AGONIST CONJUGATE AND APPLICATIONS THEREOF | GENEQUANTUM HEALTHCARE (SUZHOU) CO., LTD. (CN) | 2023-11-23 | — | — | US | disclosed |
| US-20230372511-A1 | ANTIBODY-IMMUNE AGONIST CONJUGATE AND APPLICATIONS THEREOF | GENEQUANTUM HEALTHCARE (SUZHOU) CO., LTD. (CN) | 2023-11-23 | — | — | US | disclosed |
| US-20230372500-A1 | MULTI-ARM POLYMER CONJUGATES OF TLR AGONIST COMPOUNDS AND RELATED IMMUNOTHERAPEUTIC TREATMENT METHODS | NEKTAR THERAPEUTICS (US) | 2023-11-23 | — | — | US | disclosed |
| US-20230372500-A1 | MULTI-ARM POLYMER CONJUGATES OF TLR AGONIST COMPOUNDS AND RELATED IMMUNOTHERAPEUTIC TREATMENT METHODS | NEKTAR THERAPEUTICS (US) | 2023-11-23 | — | — | US | disclosed |
| US-20230372500-A1 | MULTI-ARM POLYMER CONJUGATES OF TLR AGONIST COMPOUNDS AND RELATED IMMUNOTHERAPEUTIC TREATMENT METHODS | NEKTAR THERAPEUTICS (US) | 2023-11-23 | — | — | US | disclosed |
| US-11744898-B2 | Multi-arm polymer conjugates of TLR agonist compounds and related immunotherapeutic treatment methods | NEKTAR THERAPEUTICS (US) | 2023-09-05 | — | — | US | disclosed |
| US-20120148660-A1 | CONJUGATES OF SYNTHETIC TLR AGONISTS AND USES THEREFOR | REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN DIEGO UCSD TECHNOLOGY TRANSFER OFFICE (US) | 2012-06-14 | — | — | US | disclosed |
| US-20120148660-A1 | CONJUGATES OF SYNTHETIC TLR AGONISTS AND USES THEREFOR | REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN DIEGO UCSD TECHNOLOGY TRANSFER OFFICE (US) | 2012-06-14 | — | — | US | disclosed |
| US-20120148660-A1 | CONJUGATES OF SYNTHETIC TLR AGONISTS AND USES THEREFOR | REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN DIEGO UCSD TECHNOLOGY TRANSFER OFFICE (US) | 2012-06-14 | — | — | US | disclosed |
| CN-101790380-A | The conjugate and the application thereof of synthetic TLR agonist | UNIV CALIFORNIA | 2010-07-28 | — | — | CN | disclosed |
| US-20090324551-A1 | TLR AGONISTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA OFFICE OF TECHNOLOGY TRANSFER (US) | 2009-12-31 | — | — | US | disclosed |
| US-20090324551-A1 | TLR AGONISTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA OFFICE OF TECHNOLOGY TRANSFER (US) | 2009-12-31 | — | — | US | disclosed |
| US-20090324551-A1 | TLR AGONISTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA OFFICE OF TECHNOLOGY TRANSFER (US) | 2009-12-31 | — | — | US | disclosed |
| CN-101304748-A | Tlr agonists | UNIV CALIFORNIA (US) | 2008-11-12 | — | — | CN | disclosed |
| WO-2008115319-A2 | CONJUGATES OF SYNTHETIC TLR AGONISTS AND USES THEREFOR | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-09-25 | — | — | WO | disclosed |
| WO-2007024707-A2 | TLR AGONISTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230372500-A1 | MULTI-ARM POLYMER CONJUGATES OF TLR AGONIST COMPOUNDS AND RELATED IMMUNOTHERAPEUTIC TREATMENT METHODS | TLR7, TLR8, TLR3 | TLR7 1/4885NUDT1 1567/4885 |
| US-20230372511-A1 | ANTIBODY-IMMUNE AGONIST CONJUGATE AND APPLICATIONS THEREOF | FCGR1A, FCGR2A, TLR3 | TLR7 28/4885NUDT1 3169/4885 |
| US-20090324551-A1 | TLR AGONISTS | TLR3, TLR1, TLR5 | TLR7 6/4885NUDT1 2186/4885 |
| US-20120148660-A1 | CONJUGATES OF SYNTHETIC TLR AGONISTS AND USES THEREFOR | TLR1, TLR5, TLR8 | TLR7 4/4885NUDT1 2757/4885 |
| US-12214045-B2 | Multi-arm polymer conjugates of TLR agonist compounds and related immunotherapeutic treatment methods | TLR7, TLR8, TLR3 | TLR7 1/4885NUDT1 2266/4885 |
| US-12054553-B2 | Immunotherapeutic tumor treatment method | IL2RA, IL2, TLR3 | TLR7 6/4885NUDT1 3163/4885 |
| US-11744898-B2 | Multi-arm polymer conjugates of TLR agonist compounds and related immunotherapeutic treatment methods | TLR7, TLR8, TLR3 | TLR7 1/4885NUDT1 1598/4885 |
| US-12030940-B2 | Immunotherapeutic tumor treatment method | CD274, TLR7, PDCD1LG2 | TLR7 2/4885NUDT1 2779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.